Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24588934 | 0.95 | SLC6A4 (0.33) | ALDH1A1MEN1KMT2ASLC6A4SLC6A2 | |
| SCHEMBL24589001 | 0.95 | SLC6A4 (0.33) | ALDH1A1MEN1KMT2ASLC6A4SLC6A2 | |
| SCHEMBL16349714 | 0.95 | SLC6A4 (0.33) | ALDH1A1MEN1KMT2ASLC6A4SLC6A2 | |
| SCHEMBL24588251 | 0.95 | SLC6A4 (0.33) | ALDH1A1MEN1KMT2ASLC6A4SLC6A2 | |
| SCHEMBL8755107 | 0.87 | ALDH1A1 (0.40) | ALDH1A1CA1CA2CA4MEN1 | |
| SCHEMBL9005145 | 0.87 | ALDH1A1 (0.40) | ALDH1A1CA1CA2CA4MEN1 | |
| SCHEMBL9004832 | 0.87 | ALDH1A1 (0.40) | ALDH1A1CA1CA2CA4MEN1 | |
| SCHEMBL14156116 | 0.81 | ALDH1A1 (0.36) | ALDH1A1MEN1KMT2ALMNASLC6A4 | |
| SCHEMBL14565351 | 0.79 | SLC6A4 (0.35) | CA1CA2CA4SLC6A4 | |
| SCHEMBL24974523 | 0.76 | SIGMAR1 (0.41) | CA1CA2CA4SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022119430-A1 | STABLE COATED SOLID PHARMACEUTICAL COMPOSITION OF AN OPIOID ANALGESIC AND AN ANTI-EPILEPTIC FOR PAIN | LABORATORIOS SILANES S.A. DE C.V. (MX) | 2022-06-09 | — | — | WO | disclosed |
| EP-2617704-B1 | Phenyl substituted cycloalkylamines as monoamine reuptake inhibitors | SUNOVION PHARMACEUTICALS INC (US) | 2017-06-28 | — | — | EP | disclosed |
| US-20130046012-A1 | NEW COMPOUNDS, SYNTHESIS AND USE THEREOF IN THE TREATMENT OF PAIN | LACER, S.A. (ES) | 2013-02-21 | — | — | US | disclosed |
| US-7723341-B2 | Dihydrothienopyrimidines, suitable for the treatment of respiratory, gastrointestinal, inflammatory, nervous system disorders and/or cancer | BOEHRINGER INGELHEIM INTERNATIONAL GMBH | 2010-05-25 | — | — | US | disclosed |
| US-20090186875-A1 | Dihydrothienopyrimidines, suitable for the treatment of respiratory, gastrointestinal, inflammatory, nervous system disorders and/or cancer | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-07-23 | — | — | US | disclosed |
| EP-2060575-A1 | Dihydrothienopyrimidines and their use in treating inflammatory diseases | Boehringer Ingelheim International GmbH (DE) | 2009-05-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090186875-A1 | Dihydrothienopyrimidines, suitable for the treatment of respiratory, gastrointestinal, inflammatory, nervous system disorders and/or cancer | DPYD, DHODH, FH | ALDH1A1 47/4885CA1 3041/4885CA2 2700/4885 |
| US-20130046012-A1 | NEW COMPOUNDS, SYNTHESIS AND USE THEREOF IN THE TREATMENT OF PAIN | OPRL1, OPRK1, TRPV1 | ALDH1A1 575/4885CA1 1101/4885CA2 540/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.