Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | RAB9A | P51151 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.56 |
| ▸ | APP | P05067 | 1/20 | 0.56 |
| ▸ | GSK3B | P49841 | 1/20 | 0.55 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13343314 | 0.84 | TNFRSF1A (0.68) | ABCG2MAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL9548237 | 0.82 | MAPT (0.60) | MAPTRAB9AALDH1A1NPC1KDM4E | |
| SCHEMBL9548241 | 0.82 | MAPT (0.60) | MAPTRAB9AALDH1A1NPC1KDM4E | |
| SCHEMBL25123555 | 0.82 | GSK3B (0.75) | MAPTRAB9AALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL28132567 | 0.82 | GSK3B (0.75) | MAPTRAB9AALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL6856291 | 0.81 | HPGD (0.70) | ABCG2MAPTRAB9AALDH1A1NPC1 | |
| SCHEMBL14518414 | 0.81 | ALDH1A1 (0.70) | RAB9AALDH1A1NPC1SMN1; SMN2KMT2A | |
| SCHEMBL28549137 | 0.79 | RAB9A (0.73) | ABCG2MAPTRAB9AALDH1A1NPC1 | |
| SCHEMBL25203201 | 0.79 | RAB9A (0.70) | MAPTRAB9AALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL15971671 | 0.78 | KDM4E (0.74) | ABCG2MAPTRAB9AALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7709526-B2 | Use of cyclolignans and new cyclolignans | BIOVITRUM AB (SE) | 2010-05-04 | — | — | US | disclosed |
| US-7709526-B2 | Use of cyclolignans and new cyclolignans | BIOVITRUM AB (SE) | 2010-05-04 | — | — | US | disclosed |