Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 10/20 | 0.40 |
| ▸ | PTGER2 | P43116 | 10/20 | 0.40 |
| ▸ | MAOB | P27338 | 4/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 3/20 | 0.34 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13348388 | 0.90 | PTGER4 (0.49) | PTGER4PTGER2MAOBMAOA | |
| SCHEMBL13348239 | 0.86 | PTGER4 (0.37) | PTGER4PTGER2MAOBMAOA | |
| SCHEMBL13312095 | 0.86 | FFAR1 (0.46) | PTGER4PTGER2 | |
| SCHEMBL13348393 | 0.86 | CYP2D6 (0.37) | PTGER4PTGER2MAOBMAOASCN3A | |
| SCHEMBL13348160 | 0.85 | PTGER4 (0.48) | PTGER4PTGER2MAOBMAOA | |
| SCHEMBL13348224 | 0.84 | PTGER4 (0.46) | PTGER4PTGER2MAOBMAOA | |
| SCHEMBL13312652 | 0.82 | PTGER4 (0.41) | PTGER4PTGER2 | |
| SCHEMBL13348108 | 0.82 | AOC3 (0.38) | PTGER4PTGER2MAOBSCN3A | |
| SCHEMBL13348056 | 0.81 | FFAR1 (0.38) | PTGER4PTGER2MAOBMAOASCN3A | |
| SCHEMBL13348107 | 0.80 | PTGER4 (0.44) | PTGER4PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100152165-A1 | CARBOXYLIC ACID DERIVATIVES | ASTELLAS PHARMA INC. (JP) | 2010-06-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100152165-A1 | CARBOXYLIC ACID DERIVATIVES | GPR119, GPR65, HCAR1 | PTGER4 1432/4885PTGER2 3346/4885MAOB 3933/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.