Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 12/20 | 0.49 |
| ▸ | PTGER2 | P43116 | 12/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13348224 | 0.94 | PTGER4 (0.46) | PTGER4PTGER2CA12CA9MAOA | |
| SCHEMBL13348160 | 0.92 | PTGER4 (0.48) | PTGER4PTGER2MAOAMAOBLTA4H | |
| SCHEMBL13348167 | 0.90 | PTGER4 (0.40) | PTGER4PTGER2MAOAMAOB | |
| SCHEMBL13312087 | 0.87 | PTGER4 (0.54) | PTGER4PTGER2 | |
| SCHEMBL13348108 | 0.87 | AOC3 (0.38) | PTGER4PTGER2CA12CA9MAOB | |
| SCHEMBL13348107 | 0.86 | PTGER4 (0.44) | PTGER4PTGER2LTA4H | |
| SCHEMBL13348239 | 0.86 | PTGER4 (0.37) | PTGER4PTGER2MAOAMAOBLTA4H | |
| SCHEMBL13348393 | 0.85 | CYP2D6 (0.37) | PTGER4PTGER2MAOAMAOB | |
| SCHEMBL13348225 | 0.83 | LTA4H (0.35) | PTGER4PTGER2CA12CA9MAOB | |
| SCHEMBL13312685 | 0.82 | PTGER4 (0.49) | PTGER4PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100152165-A1 | CARBOXYLIC ACID DERIVATIVES | ASTELLAS PHARMA INC. (JP) | 2010-06-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100152165-A1 | CARBOXYLIC ACID DERIVATIVES | GPR119, GPR65, HCAR1 | PTGER4 1432/4885PTGER2 3346/4885CA12 1061/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.