⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8426937 | 0.86 | KDM4E (0.30) | — | |
| SCHEMBL13348706 | 0.72 | — | — | |
| SCHEMBL16079874 | 0.72 | — | — | |
| SCHEMBL28859299 | 0.72 | L3MBTL1 (0.37) | — | |
| SCHEMBL6255357 | 0.68 | — | — | |
| SCHEMBL4460329 | 0.68 | — | — | |
| SCHEMBL28313996 | 0.68 | BCL2 (0.39) | — | |
| SCHEMBL29089004 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL28506067 | 0.67 | GDA (0.38) | — | |
| SCHEMBL9706756 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7737284-B2 | Synthesis of temozolomide and analogs | SCHERING PLOUGH CORP. (US) | 2010-06-15 | — | — | US | disclosed |
| US-20090023919-A1 | SYNTHESIS OF TEMOZOLOMIDE AND ANALOGS | SCHERING CORPORATION | 2009-01-22 | — | — | US | disclosed |