Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.31 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | CETP | P11597 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | XDH | P47989 | 1/20 | 0.30 |
| ▸ | LCK | P06239 | 1/20 | 0.30 |
| ▸ | CTSL | P07711 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8426937 | 0.76 | KDM4E (0.30) | ALDH1A1SMN1; SMN2HPGDKDM4ETP53 | |
| SCHEMBL16211898 | 0.72 | L3MBTL1 (0.39) | L3MBTL1GAAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL13348604 | 0.72 | — | — | |
| SCHEMBL9706756 | 0.69 | — | — | |
| SCHEMBL16079874 | 0.68 | — | — | |
| SCHEMBL1177002 | 0.65 | L3MBTL1 (0.73) | L3MBTL1GAAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL8884122 | 0.65 | L3MBTL1 (0.38) | L3MBTL1ALDH1A1SMN1; SMN2HPGDNPC1 | |
| SCHEMBL13348706 | 0.64 | — | — | |
| SCHEMBL28313996 | 0.64 | BCL2 (0.39) | ALDH1A1SMN1; SMN2HPGDRAB9ALMNA | |
| SCHEMBL8720615 | 0.64 | BRD4 (0.58) | SMN1; SMN2HSD17B10NPC1TP53RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105209466-B | purine derivatives as CB2 receptor agonists | 豪夫迈·罗氏有限公司 | 2018-05-18 | — | — | CN | disclosed |