SCHEMBL8426937

SCHEMBL8426937

O=CNc1nc[nH]c1NC=O

nearest known ligand 0.30

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30
TP53 P04637 1/20 0.30
HPGD P15428 1/20 0.30
PTGS1 P23219 1/20 0.30
HBB P68871 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13348604 0.86
SCHEMBL6255357 0.77
SCHEMBL16079874 0.77
SCHEMBL13348706 0.77
SCHEMBL4460329 0.77
SCHEMBL28859299 0.76 L3MBTL1 (0.37) KDM4EALDH1A1TP53HPGDSMN1; SMN2
Hydrochloric Acid SCHEMBL28506067 0.75 GDA (0.38) KDM4E
SCHEMBL28313996 0.72 BCL2 (0.39) ALDH1A1HPGDSMN1; SMN2
SCHEMBL1059195 0.71 GDA (0.39) KDM4EALDH1A1SMN1; SMN2TDP1
SCHEMBL9706756 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109153651-A amido-substituted cyclohexane derivatives 拜耳制药股份公司 2019-01-04 CN claimed
CN-106459015-A Amido-substituted azoles as inhibitors of TNKS1 and/or TNKS2 拜耳医药股份公司 2017-02-22 CN claimed
CN-101072882-A Methods for long-range sequence analysis of nucleic acids SEQUENOM INC (US) 2007-11-14 CN claimed
CN-111809268-B Processing method of long-acting antibacterial nylon yarn 安徽三宝棉纺针织投资有限公司 2022-09-09 CN disclosed
CN-111809268-A Processing method of long-acting antibacterial nylon yarn 安徽三宝棉纺针织投资有限公司 2020-10-23 CN disclosed
CN-109153651-A amido-substituted cyclohexane derivatives 拜耳制药股份公司 2019-01-04 CN disclosed
CN-105069324-B Microarray for detecting β globulin gene variation and detection method thereof 三菱化学株式会社 2018-08-28 CN disclosed
CN-106459015-A Amido-substituted azoles as inhibitors of TNKS1 and/or TNKS2 拜耳医药股份公司 2017-02-22 CN disclosed
CN-105969848-A Microarray for detection of mutations in beta-globin genes 三菱丽阳株式会社 2016-09-28 CN disclosed
CN-104204227-B Microarray for detecting variation of beta globin gene and detection method thereof 三菱丽阳株式会社 2016-09-07 CN disclosed
CN-105069324-A Microarray for detection of mutations in beta-globin genes and detection method thereof MITSUBISHI RAYON CO 2015-11-18 CN disclosed
EP-0407554-B1 METALLIC OXIDE-OXIRANE POLYMERS AND PREPOLYMERS KEEHAN DONALD J (US) 1997-09-17 EP disclosed
US-5658996-A A LIQUID POLYEPOXIDE PREPOLYMER THE REACTION PRODUCT OF A TRISHYDROXYPHENYL, AN AROMATIC DIGLYCIDYL ETHER AND METAL OXIDE; CURABLE, LOW VISCOSITY; FORMED POLYEPOXIDE IS HEAT AND CHEMICAL RESISTANCE, ELONGATION, TOUGHNESS KEEHAN DONALD J (US) 1997-08-19 US disclosed
CN-1024887-C 2-phenylimidazole derivative-containing pesticide MAY & BAKER LTD (GB) 1994-06-08 CN disclosed
US-5169912-A Hydrolyzable oxygen bonding with epoxide; silica, titania; high performance coatings, adhesives KEEHAN DONALD J (US) 1992-12-08 US disclosed
EP-0407554-A4 METALLIC OXIDE-OXIRANE POLYMERS AND PREPOLYMERS 1992-10-21 EP disclosed
US-5026816-A Reaction product of diglycidyl ether of (bisphenol a or resorcinol) with metallic oxide in presence of imidazole catalyst KEEHAN DONALD J (US) 1991-06-25 US disclosed
EP-0407554-A1 METALLIC OXIDE-OXIRANE POLYMERS AND PREPOLYMERS. KEEHAN DONALD J (US) 1991-01-16 EP disclosed
WO-1990008168-A1 METALLIC OXIDE-OXIRANE POLYMERS AND PREPOLYMERS KEEHAN DONALD J (US) 1990-07-26 WO disclosed
CN-1030577-A Disinsection method with 2-phenylimidazole derivative MAY & BAKER CO LTD (GB) 1989-01-25 CN disclosed