Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10245926 | 0.82 | MAPT (0.43) | — | |
| SCHEMBL14314265 | 0.77 | RAB9A (0.40) | MAOBMAOA | |
| SCHEMBL14878920 | 0.77 | MAPK1 (0.37) | — | |
| SCHEMBL27881252 | 0.77 | MAOB (0.51) | MAOBKCNH2CACNA1BCYP2D6 | |
| SCHEMBL12422467 | 0.76 | CHRNB2 (0.54) | MAOBKCNH2CACNA1BCYP2D6 | |
| SCHEMBL15004555 | 0.76 | DRD2 (0.54) | MAOBKCNH2CACNA1BCYP2D6 | |
| SCHEMBL849776 | 0.74 | KMT2A (0.63) | KCNH2CACNA1B | |
| SCHEMBL28193581 | 0.74 | KCNA3 (0.62) | MAOBHDAC1HDAC2 | |
| SCHEMBL22964316 | 0.73 | FFAR1 (0.50) | MAOBMAOA | |
| SCHEMBL4160475 | 0.73 | KCNH2 (0.51) | MAOBKCNH2CACNA1BCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2194044-A1 | QUINOLONE DERIVATIVE | Astellas Pharma Inc. (JP) | 2010-06-09 | — | — | EP | disclosed |