Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL887590 | 0.81 | DAO (0.38) | MEN1KMT2AMAPT | |
| SCHEMBL13615530 | 0.78 | KMT2A (0.34) | KMT2AALDH1A1 | |
| SCHEMBL13824167 | 0.78 | ALDH1A1 (0.30) | ALDH1A1MAPT | |
| SCHEMBL28313542 | 0.69 | KMT2A (0.35) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL16575964 | 0.69 | LMNA (0.37) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL28007154 | 0.68 | SMN1; SMN2 (0.39) | MEN1KMT2A | |
| SCHEMBL309065 | 0.67 | KDM3B (0.43) | MEN1KMT2A | |
| SCHEMBL27905995 | 0.67 | MEN1 (0.33) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL12747285 | 0.67 | MET (0.35) | MEN1KMT2AALDH1A1 | |
| SCHEMBL6510859 | 0.64 | SMN1; SMN2 (0.39) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7745126-B2 | Methods, kits and compositions pertaining to combination oligomers and libraries for their preparation | BOSTON PROBES, INC. (US) | 2010-06-29 | — | — | US | disclosed |
| US-7566420-B1 | Methods, kits and compositions pertaining to combination oligomers and libraries for their preparation | BOSTON PROBES, INC. (US) | 2009-07-28 | — | — | US | disclosed |
| US-20080085837-A1 | Methods, Kits and Compositions Pertaining to Combination Oligomers and Libraries for Their Preparation | APPLERA CORPORATION (US) | 2008-04-10 | — | — | US | disclosed |
| EP-1748078-A2 | Methods, kits and compositions of combination oligomers | Boston Probes, Inc. (US) | 2007-01-31 | — | — | EP | disclosed |