Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6510859 | 0.80 | SMN1; SMN2 (0.39) | SMN1; SMN2L3MBTL1KMT2AMEN1 | |
| SCHEMBL887590 | 0.78 | DAO (0.38) | L3MBTL1KMT2AMEN1GAA | |
| SCHEMBL12747285 | 0.74 | MET (0.35) | SMN1; SMN2L3MBTL1KMT2AMEN1GAA | |
| SCHEMBL770542 | 0.72 | KMT2A (0.50) | KMT2A | |
| SCHEMBL17243359 | 0.68 | HPGD (0.46) | — | |
| SCHEMBL17243365 | 0.68 | DBH (0.42) | SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL13350400 | 0.68 | MEN1 (0.32) | KMT2AMEN1 | |
| SCHEMBL17243375 | 0.67 | MMP13 (0.50) | L3MBTL1KMT2AMEN1 | |
| SCHEMBL17243368 | 0.67 | MAPK1 (0.40) | — | |
| SCHEMBL17243355 | 0.67 | GAA (0.58) | SMN1; SMN2KMT2AMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102989012-B | Monitoring and modulating hgf/hgfr activity | GEN HOSPITAL CORP | 2015-05-13 | — | — | CN | disclosed |