Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12621871 | 0.86 | GAA (0.59) | TSHRPOLBGAAMEN1KMT2A | |
| SCHEMBL13353201 | 0.82 | LMNA (0.60) | TSHRPOLBKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL13353208 | 0.81 | PKM (0.51) | TSHRPOLBGAAMEN1KMT2A | |
| SCHEMBL12622002 | 0.77 | POLB (0.64) | TSHRPOLBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL22381081 | 0.76 | PKM (0.48) | TSHRPOLBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL12939705 | 0.75 | POLB (0.74) | TSHRPOLBGAAMEN1KMT2A | |
| SCHEMBL1974783 | 0.75 | ALDH1A1 (0.85) | TSHRPOLBGAAMEN1KMT2A | |
| SCHEMBL12626021 | 0.74 | POLB (0.58) | TSHRPOLBGAAMEN1KMT2A | |
| SCHEMBL13202848 | 0.74 | SMN1; SMN2 (1.00) | TSHRPOLBGAAMEN1KMT2A | |
| SCHEMBL20022000 | 0.74 | KMT2A (1.00) | TSHRPOLBGAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010051476-A1 | FILAMIN A-BINDING ANTI-INFLAMMATORY ANALGESIC | PAIN THERAPEUTICS, INC. (US) | 2010-05-06 | — | — | WO | disclosed |