Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12621830 | 0.87 | ALDH1A1 (0.59) | LMNAALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL12622116 | 0.85 | ALDH1A1 (0.57) | LMNAALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL12624085 | 0.85 | ALDH1A1 (0.57) | LMNAALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL12624082 | 0.84 | ALDH1A1 (0.56) | LMNAALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL12624079 | 0.82 | ALDH1A1 (0.53) | LMNAALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL13353089 | 0.82 | TSHR (0.58) | ALDH1A1SMN1; SMN2TSHRUSP2KDM4E | |
| SCHEMBL13353208 | 0.81 | PKM (0.51) | ALDH1A1SMN1; SMN2TSHRUSP2KDM4E | |
| SCHEMBL20362792 | 0.80 | ALDH1A1 (0.51) | LMNAALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL12626162 | 0.80 | GLA (0.56) | LMNAALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL12622095 | 0.80 | L3MBTL1 (0.68) | LMNAALDH1A1MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010051476-A1 | FILAMIN A-BINDING ANTI-INFLAMMATORY ANALGESIC | PAIN THERAPEUTICS, INC. (US) | 2010-05-06 | — | — | WO | disclosed |