SCHEMBL660306

SCHEMBL660306

O=C(ON1C(=O)CCC1=O)c1ccccc1.O=C1C=CC(=O)N1

nearest known ligand 0.46

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 2/20 0.46
KMT2A Q03164 6/20 0.44
LMNA P02545 2/20 0.39
F2 P00734 1/20 0.39
MAPK1 P28482 2/20 0.39
PARL Q9H300 1/20 0.38
TSHR P16473 2/20 0.38
ALOX12 P18054 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
MEN1 O00255 1/20 0.38
MAPT P10636 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.36
GAA P10253 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL133554 0.89 KMT2A (0.53) MGLLKMT2ALMNAF2MAPK1
SCHEMBL19309377 0.89 KMT2A (0.53) MGLLKMT2ALMNAF2MAPK1
SCHEMBL15169077 0.83 KMT2A (0.48) MGLLKMT2ALMNAF2MAPK1
SCHEMBL15169078 0.83 KMT2A (0.48) MGLLKMT2ALMNAF2MAPK1
SCHEMBL76714 0.83 KMT2A (0.48) MGLLKMT2ALMNAF2MAPK1
SCHEMBL300884 0.80 CA12 (0.42) MGLLKMT2ALMNAMAPK1PARL
SCHEMBL4872950 0.80 SMN1; SMN2 (0.54) MGLLKMT2AMAPK1PARLMAPT
SCHEMBL20027226 0.78 KMT2A (0.47) MGLLKMT2ALMNAF2MAPK1
SCHEMBL29065830 0.77 PARL (0.48) MGLLKMT2AMAPK1PARLALOX12
SCHEMBL27717830 0.77 CA1 (0.55) MGLLKMT2ATSHRMAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016205144-A1 COMPOSITIONS OF PLATELET-DERIVED THERANOSTICS AND USES THEREOF BLUECIRCLE THERAPEUTICS, INC. (US) 2016-12-22 WO disclosed
US-20120046451-A1 ANTI-lgSF4 ANTIBODY AND UTILIZATION OF THE SAME INSTITUTE FOR ANTIBODIES CO., LTD. (JP) 2012-02-23 US disclosed
US-8048992-B2 Anti-IgSF4 antibody and utilization of the same INSTITUTE FOR ANTIBODIES CO., LTD. (JP) 2011-11-01 US disclosed
EP-1860119-B1 ANTI-IgSF4 ANTIBODY AND UTILIZATION OF THE SAME INST ANTIBODIES CO LTD (JP) 2011-08-03 EP disclosed
US-7776538-B2 Method for diagnosing methamphetamine dependence NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) 2010-08-17 US disclosed
US-20090155778-A1 Mental Disorder-Related Gene and Use of the Same NATIONAL UNIVERSITY CORPORATION NAGOYA (JP) 2009-06-18 US disclosed
US-20090053243-A1 Anti-IgSF4 Antibody and Utilization of the Same INSTITUTE FOR ANTIBODIES CO., LTD (JP) 2009-02-26 US disclosed
EP-1860119-A1 ANTI-IgSF4 ANTIBODY AND UTILIZATION OF THE SAME Institute for Antibodies Co., Ltd. (JP) 2007-11-28 EP disclosed
US-20060194268-A1 Method for measuring spinorphin MARUISHI PHARMACEUTICAL CO., LTD. (JP) 2006-08-31 US disclosed