Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 2/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 3/20 | 0.37 |
| ▸ | MAOB | P27338 | 3/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3253957 | 0.98 | LOXL2 (0.43) | LOXL2GFERKCNJ1KCNH2DAO | |
| SCHEMBL10890416 | 0.78 | CASP1 (0.46) | GFERCYP19A1TSHRHSD17B10MAOA | |
| SCHEMBL3245628 | 0.77 | CYP1A2 (0.50) | GFERKCNH2DAOCYP19A1CYP2A6 | |
| SCHEMBL4810025 | 0.77 | ESR1 (0.52) | GFERCYP19A1L3MBTL1HSD17B10MAOA | |
| SCHEMBL4810383 | 0.77 | MAOB (0.59) | LOXL2GFERCYP19A1CYP2A6HSD17B10 | |
| Hydrochloric Acid SCHEMBL3244731 | 0.76 | BLM (0.52) | GFERCYP19A1L3MBTL1HSD17B10MAOA | |
| SCHEMBL1004267 | 0.75 | LOXL2 (0.64) | LOXL2KCNJ1KCNH2DAOCYP19A1 | |
| Hydrochloric Acid SCHEMBL3251098 | 0.75 | MAOB (0.61) | LOXL2GFERCYP19A1CYP2A6TSHR | |
| SCHEMBL14193178 | 0.75 | MAOB (0.52) | GFERKCNH2DAOCYP19A1HSD17B10 | |
| SCHEMBL9642642 | 0.74 | LOXL2 (0.54) | LOXL2GFERKCNJ1KCNH2IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1685091-B1 | M-DIAMINOBENZOLES AND THE ACIDIC ADDUCTS THEREOF AND USE THEREOF IN COLOURING AGENTS | PROCTER & GAMBLE (US) | 2010-05-19 | — | — | EP | disclosed |
| US-7361198-B2 | M-diaminobenzenes, their acid adducts and the use thereof in colorants | WELLA AG (DE) | 2008-04-22 | — | — | US | disclosed |