Biphenyl

Biphenyl

SCHEMBL29090175

NC=O.c1ccc(-c2ccccc2)cc1.c1cnc2cccnc2c1

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.46
NOTUM Q6P988 1/20 0.44
NPC1 O15118 3/20 0.42
TOP1 P11387 2/20 0.41
MAOB P27338 1/20 0.39
CYP2A6 P11509 1/20 0.38
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA9 Q16790 1/20 0.38
KDM4E B2RXH2 1/20 0.38
MAPT P10636 1/20 0.38
PIK3CA P42336 1/20 0.38
ERN1 O75460 1/20 0.37
RAB9A P51151 2/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
POLB P06746 1/20 0.36
TGFBR1 P36897 1/20 0.36
NCF1 P14598 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Formamide SCHEMBL27359672 0.89 ALDH1A1 (0.50) ALDH1A1NPC1KDM4EMAPTERN1
Biphenyl SCHEMBL29127776 0.85 ALDH1A1 (0.52) ALDH1A1NOTUMNPC1TOP1MAOB
Biphenyl SCHEMBL28549078 0.85 ALDH1A1 (0.52) ALDH1A1NOTUMNPC1TOP1MAOB
Quinoxaline SCHEMBL1335895 0.84 ALDH1A1 (0.44) ALDH1A1NPC1KDM4EMAPTERN1
Quinoline SCHEMBL1337002 0.81 ALDH1A1 (0.74) ALDH1A1NPC1KDM4EMAPTRAB9A
Biphenyl SCHEMBL3096874 0.79 ALDH1A1 (0.53) ALDH1A1NOTUMNPC1TOP1PIK3CA
Biphenyl SCHEMBL7723103 0.79 ALDH1A1 (0.60) ALDH1A1NOTUMCYP2A6CA12CA1
Benzene SCHEMBL27857732 0.76 ALDH1A1 (0.63) ALDH1A1NPC1KDM4EMAPTRAB9A
Quinoxaline SCHEMBL28165605 0.76 NOTUM (0.71) ALDH1A1NOTUMNPC1KDM4EMAPT
Biphenyl SCHEMBL4922682 0.76 ALDH1A1 (0.81) ALDH1A1NOTUMNPC1TOP1CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116890555-A High-temperature-resistant thermosensitive medical film with stable imaging and preparation process thereof 江苏普仁新材料科技有限公司 2023-10-17 CN disclosed