Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | CTSS | P25774 | 2/20 | 0.54 |
| ▸ | CTSK | P43235 | 2/20 | 0.54 |
| ▸ | CTSL | P07711 | 1/20 | 0.54 |
| ▸ | PDE4A | P27815 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | GALR2 | O43603 | 1/20 | 0.44 |
| ▸ | GALR1 | P47211 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13326000 | 0.91 | RAB9A (0.70) | RAB9AKDM4ENFKB1CTSSCTSK | |
| SCHEMBL13326006 | 0.84 | RAB9A (0.74) | RAB9ACTSSCTSKCTSLPDE4A | |
| SCHEMBL13359703 | 0.83 | CTSS (0.59) | RAB9ACTSSCTSKCTSLMAPT | |
| SCHEMBL13359701 | 0.83 | NFKB1 (0.77) | RAB9AKDM4ENFKB1MAPTSMN1; SMN2 | |
| SCHEMBL13325999 | 0.82 | RAB9A (0.61) | RAB9AKDM4ENFKB1CTSSCTSK | |
| SCHEMBL3503380 | 0.80 | RAB9A (0.80) | RAB9ACTSSCTSKCTSLPDE4A | |
| SCHEMBL14600703 | 0.78 | RAB9A (0.75) | RAB9ANFKB1CTSSCTSKCTSL | |
| SCHEMBL20938665 | 0.78 | RAB9A (0.75) | RAB9ANFKB1CTSSCTSKCTSL | |
| SCHEMBL13326008 | 0.78 | RAB9A (0.75) | RAB9ANFKB1CTSSCTSKCTSL | |
| SCHEMBL13752158 | 0.77 | NR5A1 (0.54) | RAB9AKDM4ENFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7718655-B2 | Trisubstituted triazine compounds, and methods for making and using the compounds, which have antitubulin activity | NEW YORK UNIVERSITY (US) | 2010-05-18 | — | — | US | disclosed |