Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 3/20 | 0.59 |
| ▸ | CTSK | P43235 | 3/20 | 0.59 |
| ▸ | CTSL | P07711 | 2/20 | 0.59 |
| ▸ | GALR2 | O43603 | 5/20 | 0.49 |
| ▸ | GALR1 | P47211 | 5/20 | 0.49 |
| ▸ | MERTK | Q12866 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.45 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3290227 | 0.92 | CTSL (0.61) | CTSSCTSKCTSLGALR2GALR1 | |
| SCHEMBL3289389 | 0.92 | CTSL (0.68) | CTSSCTSKCTSLGALR2GALR1 | |
| SCHEMBL3287006 | 0.86 | CTSL (0.61) | CTSSCTSKCTSLGALR2GALR1 | |
| SCHEMBL3289272 | 0.86 | CTSL (0.57) | CTSSCTSKCTSLGALR2GALR1 | |
| SCHEMBL3287378 | 0.85 | CTSS (0.56) | CTSSCTSKCTSLGALR2GALR1 | |
| SCHEMBL13325957 | 0.84 | CTSS (0.54) | CTSSCTSKCTSLGALR2GALR1 | |
| SCHEMBL13359702 | 0.83 | RAB9A (0.67) | CTSSCTSKCTSLGALR2GALR1 | |
| SCHEMBL3290340 | 0.83 | CTSL (0.57) | CTSSCTSKCTSLGALR2GALR1 | |
| SCHEMBL3291713 | 0.82 | GALR2 (0.67) | CTSSCTSKCTSLGALR2GALR1 | |
| SCHEMBL3287809 | 0.81 | CTSL (0.54) | CTSSCTSKCTSLGALR2GALR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7718655-B2 | Trisubstituted triazine compounds, and methods for making and using the compounds, which have antitubulin activity | NEW YORK UNIVERSITY (US) | 2010-05-18 | — | — | US | disclosed |