Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.62 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9609808 | 0.85 | SMN1; SMN2 (0.82) | SMN1; SMN2HPGDMAPTALDH1A1KMT2A | |
| SCHEMBL13885934 | 0.82 | CYP17A1 (0.50) | SMN1; SMN2ALDH1A1HSD17B10KMT2A | |
| SCHEMBL14435186 | 0.79 | SMN1; SMN2 (0.56) | SMN1; SMN2HPGDMAPTALDH1A1KMT2A | |
| SCHEMBL15500757 | 0.79 | SMN1; SMN2 (0.56) | SMN1; SMN2HPGDMAPTALDH1A1KMT2A | |
| SCHEMBL8778393 | 0.79 | MAPT (0.63) | SMN1; SMN2HPGDMAPTALDH1A1HSD17B10 | |
| SCHEMBL7251623 | 0.79 | SMN1; SMN2 (0.72) | SMN1; SMN2HPGDMAPTALDH1A1RAB9A | |
| SCHEMBL12808545 | 0.78 | HPGD (0.65) | SMN1; SMN2HPGDMAPTALDH1A1KMT2A | |
| SCHEMBL28442623 | 0.78 | SMN1; SMN2 (0.55) | SMN1; SMN2HPGDMAPTRAB9ANPC1 | |
| SCHEMBL21431105 | 0.78 | PRSS1 (0.54) | SMN1; SMN2MAPTALDH1A1KMT2ARAB9A | |
| SCHEMBL514571 | 0.77 | SMN1; SMN2 (0.69) | SMN1; SMN2HPGDMAPTALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100113371-A9 | Derivatives Of Pentose Monosaccharides As Anti-Inflammatory Compounds | RANBAXY LABORATORIES LIMITED INC. (IN) | 2010-05-06 | — | — | US | disclosed |
| US-20090221515-A1 | MONOSACCHARIDE DERIVATIVES | RANBAXY LABORATORIES INC. (IN) | 2009-09-03 | — | — | US | disclosed |
| US-20090075909-A1 | Derivatives Of Pentose Monosaccharides As Anti-Inflammatory Compounds | RANBAXY LABORATORIES LIMITED INC. (IN) | 2009-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090075909-A1 | Derivatives Of Pentose Monosaccharides As Anti-Inflammatory Compounds | HLA-DRB1, IL5, TNF | SMN1; SMN2 4524/4885HPGD 2643/4885MAPT 728/4885 |
| US-20090221515-A1 | MONOSACCHARIDE DERIVATIVES | HLA-DRB1, MUC1, FUT5 | SMN1; SMN2 4797/4885HPGD 2833/4885MAPT 1370/4885 |
| US-20100113371-A9 | Derivatives Of Pentose Monosaccharides As Anti-Inflammatory Compounds | HLA-DRB1, IL5, TNF | SMN1; SMN2 4524/4885HPGD 2643/4885MAPT 728/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.