Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 5/20 | 0.50 |
| ▸ | NOTUM | Q6P988 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MPI | P34949 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | KIT | P10721 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | KMO | O15229 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1646236 | 0.86 | GP6 (0.37) | IDO1RAB9AALDH1A1 | |
| SCHEMBL6163475 | 0.80 | TSHR (0.35) | IDO1TSHRSMN1; SMN2MAOBALDH1A1 | |
| SCHEMBL23457513 | 0.80 | AHR (0.45) | IDO1NOTUMNPC1NFKB1RAB9A | |
| SCHEMBL29699397 | 0.80 | AHR (0.45) | IDO1NOTUMNPC1NFKB1RAB9A | |
| SCHEMBL29699377 | 0.79 | CYP2A6 (0.39) | ALDH1A1PDGFRBKDRDYRK1A | |
| SCHEMBL13896466 | 0.78 | IDO1 (0.50) | IDO1NOTUMTP53NFKB1NFKB2 | |
| SCHEMBL5613019 | 0.78 | METAP2 (0.50) | IDO1MAPK13 | |
| SCHEMBL917247 | 0.78 | IDO1 (0.46) | IDO1 | |
| SCHEMBL4831837 | 0.78 | HSD17B1 (0.53) | FYN | |
| SCHEMBL4313886 | 0.78 | METAP2 (0.50) | NPC1TSHRRAB9AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050143578-A1 | Compounds and methods | SMITHKLINE BEECHAM CORPORATION | 2005-06-30 | — | — | US | claimed |
| EP-1434772-A4 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORP (US) | 2005-05-04 | — | — | EP | claimed |
| US-20040192914-A1 | Compounds and methods | SMITHKLINE BEECHAM CORPORATION | 2004-09-30 | — | — | US | claimed |
| EP-1434772-A1 | COMPOUNDS AND METHODS | SmithKline Beecham Corporation (US) | 2004-07-07 | — | — | EP | claimed |
| WO-2003031434-A1 | COMPOUNDS AND METHODS | SMITH KLINE BEECHAM CORPORATION (US) | 2003-04-17 | — | — | WO | claimed |
| EP-0958287-A1 | SULFAMIDE-METALLOPROTEASE INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 1999-11-24 | — | — | EP | claimed |
| WO-1998032748-A1 | SULFAMIDE-METALLOPROTEASE INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 1998-07-30 | — | — | WO | claimed |
| WO-2023122498-A1 | ONE-STEP OXIDE BATH FOR IMPROVING ADHESION OF POLYMERIC MATERIALS TO METAL SUBSTRATES | MACDERMID, INCORPORATED (US) | 2023-06-29 | — | — | WO | disclosed |
| US-9550757-B2 | Nuclear transport modulators and uses thereof | Karyopharm Therapeutics Inc. (US) | 2017-01-24 | — | — | US | disclosed |
| EP-2542089-B1 | NUCLEAR TRANSPORT MODULATORS AND USES THEREOF | KARYOPHARM THERAPEUTICS INC (US) | 2017-01-18 | — | — | EP | disclosed |
| US-20140155370-A1 | NUCLEAR TRANSPORT MODULATORS AND USES THEREOF | Karyopharm Therapeutics Inc. | 2014-06-05 | — | — | US | disclosed |
| US-20140004071-A1 | Thermochromic Dental Material | BROWN WILLIAM STEVEN (US) | 2014-01-02 | — | — | US | disclosed |
| US-8513230-B2 | Nuclear transport modulators and uses thereof | KARYOPHARM THERAPEUTICS, INC. (US) | 2013-08-20 | — | — | US | disclosed |
| EP-0901040-A1 | Substiantially light-insensitive thermographic recording material with improved stability and image-tone | AGFA-GEVAERT N.V. (BE) | 1999-03-10 | — | — | EP | disclosed |
| EP-0809142-A1 | Production process for a thermographic recording material with improved stability and image-tone | AGFA-GEVAERT N.V. (BE) | 1997-11-26 | — | — | EP | disclosed |
| CN-1163189-A | Lens in eye and its producing method | HOYA CORP (JP) | 1997-10-29 | — | — | CN | disclosed |
| US-5663034-A | BLACK AND WHITE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-09-02 | — | — | US | disclosed |
| US-5063139-A | Silver halide color photographic light-sensitive material capable of being processed at ultrahigh speed and process for the formation of color images using thereof | FUJI PHOTO FILM CO., LTD. (JP) | 1991-11-05 | — | — | US | disclosed |
| EP-0324391-A2 | Method for the formation of high-contrast images | KONICA CORPORATION (JP) | 1989-07-19 | — | — | EP | disclosed |
| EP-0255721-A2 | Silver halide emulsions and photographic materials | FUJI PHOTO FILM CO., LTD. (JP) | 1988-02-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040192914-A1 | Compounds and methods | METAP2, METAP1, DNPEP | IDO1 300/4885NOTUM 121/4885NPC1 3027/4885 |
| US-20140155370-A1 | NUCLEAR TRANSPORT MODULATORS AND USES THEREOF | XPO1, NXF1, XPOT | IDO1 2852/4885NOTUM 4789/4885NPC1 146/4885 |
| US-20050143578-A1 | Compounds and methods | METAP2, METAP1, DNPEP | IDO1 316/4885NOTUM 162/4885NPC1 3179/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.