Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Betaine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL150282 | 0.87 | HDAC8 (0.42) | HDAC8ACHEALDH1A1 | |
| SCHEMBL29461432 | 0.87 | HDAC8 (0.42) | HDAC8ACHEALDH1A1 | |
| Water SCHEMBL29558803 | 0.85 | HDAC8 (0.41) | HDAC8ACHEALDH1A1 | |
| Water SCHEMBL869251 | 0.85 | HDAC8 (0.41) | HDAC8ACHEALDH1A1 | |
| SCHEMBL1560289 | 0.83 | HDAC8 (0.41) | HDAC8ACHE | |
| Water SCHEMBL8976458 | 0.81 | HDAC8 (0.40) | HDAC8ACHE | |
| Betaine SCHEMBL953768 | 0.79 | TDP1 (0.36) | HDAC8ACHETSHRALDH1A1LMNA | |
| Betaine SCHEMBL6128659 | 0.79 | KCNH2 (0.34) | TSHRALDH1A1LMNAMAPK1 | |
| SCHEMBL7057933 | 0.79 | HDAC8 (0.44) | HDAC8ACHETSHRALDH1A1 | |
| SCHEMBL12223395 | 0.78 | HDAC8 (0.41) | HDAC8ACHEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 835 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3802629-B1 | METHODS FOR REDUCING OR PREVENTING COLLOIDS ADHESION AND/OR FOULING ON A SUBSTRATE, COMPOSITIONS, AND COPOLYMERS USEFUL THEREFOR | SPECIALTY OPERATIONS FRANCE (FR) | 2024-05-01 | — | — | EP | claimed |
| CN-114364708-B | Method, composition and copolymer for use in the same for combating frost on a substrate | 罗地亚经营管理公司 | 2024-04-26 | — | — | CN | claimed |
| CN-117448899-A | Electroplating solution, electroplating process and printed circuit board | 上海天承化学有限公司 | 2024-01-26 | — | — | CN | claimed |
| US-11873280-B2 | Cross-linking agent(s) | GL CHEMTEC VISION INC. (CA) | 2024-01-16 | — | — | US | claimed |
| WO-2024003352-A1 | USE OF POLYMER ADDITIVE COMPRISING ZWITTERIONIC MOIETIES IN PVDF MEMBRANES FOR DECREASING THE TRANSMEMBRANE PRESSURE AT CONSTANT FLUX OF SAID MEMBRANES | SOLVAY SA (BE) | 2024-01-04 | — | — | WO | claimed |
| WO-2024003351-A1 | USE OF POLYMER ADDITIVE COMPRISING ZWITTERIONIC MOIETIES IN PVDF MEMBRANES FOR INCREASING THE FLUX OF SAID MEMBRANES | SOLVAY SA (BE) | 2024-01-04 | — | — | WO | claimed |
| EP-3990556-A1 | USE OF POLYPHENOL COMPOUNDS AND HYDROPHILIC POLYMERS FOR REDUCING OR PREVENTING COLLOIDS ADHESION AND/OR FOULING ON A SUBSTRATE | RHODIA OPERATIONS (FR) | 2022-05-04 | — | — | EP | claimed |
| WO-2021122628-A1 | POLYMER ADDITIVE COMPRISING ZWITTERIONIC MOIETIES FOR PVDF BASED MEMBRANES | SOLVAY SA (BE) | 2021-06-24 | — | — | WO | claimed |
| EP-3838387-A1 | POLYMER ADDITIVE COMPRISING ZWITTERIONIC MOIETIES FOR PVDF BASED MEMBRANES | Solvay SA (BE) | 2021-06-23 | — | — | EP | claimed |
| US-11008538-B2 | Reduced misting alkaline and neutral cleaning, sanitizing, and disinfecting compositions via the use of high molecular weight water-in-oil emulsion polymers | ECOLAB USA INC. (US) | 2021-05-18 | — | — | US | claimed |
| WO-2003014276-A1 | CLEANING COMPOSITIONS CONTAINING NANOLATEX, PEROXYGEN BLEACH AND/OR FLUORINATED COMPOUNDS AND METHOD FOR CLEANING CARPETS | THE PROCTER & GAMBLE COMPANY (US) | 2003-02-20 | — | — | WO | claimed |
| WO-2003006596-A1 | CLEANING COMPOSITIONS AND METHOD FOR CLEANING CARPETS AND OTHER MATERIALS | THE PROCTER & GAMBLE COMPANY (US) | 2003-01-23 | — | — | WO | claimed |
| WO-2003006595-A1 | METHOD FOR CLEANING A SURFACE WITH AN AQUEOUS COMPOSITION CONTAINING A DISPERSED POLYMER | RHODIA CHIMIE (FR) | 2003-01-23 | — | — | WO | claimed |
| US-20020065208-A1 | Composition based on nanoparticles or a nanolatex of polymers for fabric care | PROCTER & GAMBLE COMPAMY, THE | 2002-05-30 | — | — | US | claimed |
| WO-2002018451-A2 | COMPOSITION BASED ON NANOPARTICLES OR NANOLATEX OF POLYMERS FOR TREATING LINEN | RHODIA CHIMIE (FR) | 2002-03-07 | — | — | WO | claimed |
| US-5415685-A | Electroplating bath and process for white palladium | ENTHONE-OMI INC. (US) | 1995-05-16 | — | — | US | claimed |
| EP-0253254-B1 | DISPERSION POLYMERS, BIOLOGICALLY ACTIVE DISPERSION POLYMERS, THEIR PREPARATION PROCESS AND THEIR USE AS A DIAGNOSTIC MEAN | BEHRINGWERKE Aktiengesellschaft (DE) | 1991-09-11 | — | — | EP | claimed |
| EP-0209337-B1 | ADHESIVES | Smith & McLaurin Ltd. (GB) | 1991-03-06 | — | — | EP | claimed |
| US-4921915-A | Dispersion polymers, biologically active dispersion polymers, a process for their preparation, and their use as diagnostic aids | BEHRINGWERKE AKTIENGESELLSCHAFT (DE) | 1990-05-01 | — | — | US | claimed |
| EP-0209337-A2 | Adhesives | Smith & McLaurin Ltd. (GB) | 1987-01-21 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11873280-B2 | Cross-linking agent(s) | WASF2, ITK, MACF1 | HDAC8 721/4885ACHE 596/4885TSHR 3721/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.