⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28178533 | 0.79 | CES2 (0.35) | — | |
| SCHEMBL28178528 | 0.78 | CES2 (0.34) | — | |
| SCHEMBL28178532 | 0.73 | S1PR1 (0.34) | — | |
| Formaldehyde SCHEMBL28680174 | 0.65 | CYP2A6 (0.62) | — | |
| SCHEMBL2125063 | 0.65 | CYP2A6 (0.72) | — | |
| SCHEMBL15080591 | 0.63 | — | — | |
| SCHEMBL2166098 | 0.61 | CES2 (0.71) | — | |
| SCHEMBL3272540 | 0.61 | HTR6 (0.39) | — | |
| SCHEMBL2877856 | 0.61 | — | — | |
| SCHEMBL6381365 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 731 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190016745-A1 | AMINOGLYCOSIDE DERIVATIVES AND USES THEREOF IN TREATING MICROBIAL INFECTIONS | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) | 2019-01-17 | — | — | US | claimed |
| EP-3400231-A1 | AMINOGLYCOSIDE DERIVATIVES AND USES THEREOF IN TREATING MICROBIAL INFECTIONS | Technion Research & Development Foundation Limited (IL) | 2018-11-14 | — | — | EP | claimed |
| EP-3344641-A1 | AMINOGLYCOSIDE DERIVATIVES AND USES THEREOF IN TREATING GENETIC DISORDERS | Eloxx Pharmaceuticals Ltd. (IL) | 2018-07-11 | — | — | EP | claimed |
| CN-105061270-B | One kind is containing fluorene structured light-cured resin of the double thiophenyls of many ethyoxyls and preparation method thereof | 东莞市贝特利新材料有限公司 | 2017-08-01 | — | — | CN | claimed |
| WO-2017118967-A1 | AMINOGLYCOSIDE DERIVATIVES AND USES THEREOF IN TREATING MICROBIAL INFECTIONS | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) | 2017-07-13 | — | — | WO | claimed |
| WO-2017037719-A1 | AMINOGLYCOSIDE DERIVATIVES AND USES THEREOF IN TREATING GENETIC DISORDERS | ELOXX PHARMACEUTICALS LTD. (IL) | 2017-03-09 | — | — | WO | claimed |
| EP-3049072-A1 | SYNTHESIS OF DELTA 12-PGJ3 AND RELATED COMPOUNDS | William Marsh Rice University (US) | 2016-08-03 | — | — | EP | claimed |
| CN-105061270-A | Light-cured resin containing polyethoxy bisthiophenyl fluorene structure and preparation method thereof | DONGGUAN CITY BETTERLY NEW MATERIALS CO LTD | 2015-11-18 | — | — | CN | claimed |
| WO-2015048268-A1 | SYNTHESIS OF DELTA 12-PGJ3 AND RELATED COMPOUNDS | WILLIAM MARSH RICE UNIVERSITY (US) | 2015-04-02 | — | — | WO | claimed |
| EP-0436199-B1 | Cyclopropyl derivative lipoxygenase inhibitors | ABBOTT LAB (US) | 1994-08-03 | — | — | EP | claimed |
| EP-0142694-A1 | 4-Substituted-delta-2-imidazolinyl-thio ethers, and process for their production | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-05-29 | — | — | EP | claimed |
| EP-0142027-A1 | 5-Substituted-delta-2-imidazolinyl-thio ethers, and process for their production | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-05-22 | — | — | EP | claimed |
| EP-0034778-B1 | HETERO-IMINO-PROSTACYCLINS AND PROCESS FOR THEIR PREPARATION | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-04-25 | — | — | EP | claimed |
| EP-0008077-B1 | PROSTAGLANDIN DERIVATIVES WITH A DELTA-2-PGF2 STRUCTURE OR A DELTA-2-PGE2 STRUCTURE, PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-11-16 | — | — | EP | claimed |
| US-4371542-A | Hetero-imino-prostacyclins | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-02-01 | — | — | US | claimed |
| US-4304783-A | ANTITHROMBOTIC, ANTIINFARCT, HYPOTENSIVE AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-12-08 | — | — | US | claimed |
| US-4296121-A | HYPOTENSIVE AGENTS, ANTICOAGULANTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-10-20 | — | — | US | claimed |
| US-4264623-A | HYPOTENSIVE AGENTS | ROUSSEL UCLAF (FR) | 1981-04-28 | — | — | US | claimed |
| EP-0012072-A2 | Beta-lactones derived from 2-hydroxycyclopentane carboxylic acid, process for their preparation and pharmaceutical compositions containing them | ROUSSEL-UCLAF (FR) | 1980-06-11 | — | — | EP | claimed |
| US-4119777-A | BY OXIDATION OF A THIOAMIDE DERIVATIVE | FUJI PHOTO FILM CO., LTD. (JP) | 1978-10-10 | — | — | US | claimed |