Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 6/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | EDNRA | P25101 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MPO | P05164 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CCR4 | P51679 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5482437 | 0.89 | HTR6 (0.61) | HTR6HSD11B1ALDH1A1TSHR | |
| SCHEMBL15285333 | 0.85 | GAA (0.64) | L3MBTL1CYP3A4ALDH1A1CYP2C9GAA | |
| SCHEMBL15285362 | 0.80 | CA2 (0.48) | HTR6L3MBTL1ALDH1A1GAA | |
| SCHEMBL15287831 | 0.80 | PKM (0.68) | L3MBTL1HSD11B1ALDH1A1GAA | |
| SCHEMBL11387848 | 0.79 | L3MBTL1 (0.36) | HTR6L3MBTL1CES2CES1EDNRA | |
| SCHEMBL16795 | 0.79 | — | — | |
| SCHEMBL1035591 | 0.79 | — | — | |
| SCHEMBL6217014 | 0.79 | — | — | |
| SCHEMBL3437251 | 0.79 | — | — | |
| SCHEMBL1322510 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0302321-A2 | Process for the preparation of thiophenols, and these thiophenols | BAYER AG (DE) | 1989-02-08 | — | — | EP | claimed |
| CN-111801355-B | Polymer material and method for producing same | 国立大学法人大阪大学 | 2023-02-28 | — | — | CN | disclosed |
| WO-2021045203-A1 | POLYMER MATERIAL AND PRODUCTION METHOD THEREFOR | 国立大学法人大阪大学 | 2021-03-11 | — | — | WO | disclosed |
| CN-111801355-A | Polymer material and method for producing same | 国立大学法人大阪大学 | 2020-10-20 | — | — | CN | disclosed |
| EP-1292308-B1 | ALPHA,BETA-UNSATURATED SULFONES FOR TREATING PROLIFERATIVE DISORDERS | UNIV TEMPLE (US) | 2010-06-09 | — | — | EP | disclosed |
| EP-1292308-A4 | ALPHA,BETA-UNSATURATED SULFONES FOR TREATING PROLIFERATIVE DISORDERS | UNIV TEMPLE (US) | 2005-09-14 | — | — | EP | disclosed |
| US-6599932-B1 | Highly selective in killing tumor cells but not normal cells | TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | 2003-07-29 | — | — | US | disclosed |
| US-20030130339-A1 | ALPHA, BETA-UNSATURATED SULFONES FOR TREATING PROLIFERATIVE DISORDERS | REDDY E PREMKUMAR (US) | 2003-07-10 | — | — | US | disclosed |
| US-6541475-B2 | 2-nitrostyryl-1-(naphthylmethyl)sulfone for example | TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | 2003-04-01 | — | — | US | disclosed |
| EP-1292308-A1 | ALPHA,BETA-UNSATURATED SULFONES FOR TREATING PROLIFERATIVE DISORDERS | Temple University of the Commonwealth System of Higher Education (US) | 2003-03-19 | — | — | EP | disclosed |
| US-20020028818-A1 | Alpha, beta-unsaturated sulfones for treating proliferative disorders | TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | 2002-03-07 | — | — | US | disclosed |
| WO-2001078733-A1 | ALPHA,BETA-UNSATURATED SULFONES FOR TREATING PROLIFERATIVE DISORDERS | TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2001-10-25 | — | — | WO | disclosed |
| US-4980510-A | REACTING A SUBSTITUTED HALOBENZENE WITH SODIUM HYDROSULFIDE OR SODIUM SULFIDE AND ACIDIFICATION | BAYER AKTIENGESELLSCHAFT (DE) | 1990-12-25 | — | — | US | disclosed |
| EP-0302321-A2 | Process for the preparation of thiophenols, and these thiophenols | BAYER AG (DE) | 1989-02-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020028818-A1 | Alpha, beta-unsaturated sulfones for treating proliferative disorders | QSOX1, CBR1, DEGS1 | HTR6 2771/4885L3MBTL1 2727/4885CES2 2359/4885 |
| US-20030130339-A1 | ALPHA, BETA-UNSATURATED SULFONES FOR TREATING PROLIFERATIVE DISORDERS | QSOX1, CCNY, CBR1 | HTR6 3903/4885L3MBTL1 2056/4885CES2 2438/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.