Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NPY1R | P25929 | 1/20 | 0.35 |
| ▸ | NPY2R | P49146 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13367229 | 0.86 | KDM5B (0.41) | L3MBTL1GAAKDM4ENPC1RAB9A | |
| SCHEMBL12225690 | 0.84 | PKM (0.38) | MAPTPKML3MBTL1GAAALDH1A1 | |
| SCHEMBL16350295 | 0.79 | CYP3A4 (0.36) | MAPTL3MBTL1GAAALDH1A1SMN1; SMN2 | |
| SCHEMBL12225694 | 0.79 | ADORA2A (0.41) | MAPTPKML3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL12225281 | 0.77 | LMNA (0.47) | MAPTL3MBTL1GAAALDH1A1SMN1; SMN2 | |
| SCHEMBL12140417 | 0.76 | MAPT (0.39) | MAPTL3MBTL1GAAALDH1A1SMN1; SMN2 | |
| SCHEMBL12225691 | 0.69 | THRB (0.34) | MAPTPKMALDH1A1SMN1; SMN2THRA | |
| SCHEMBL12225744 | 0.69 | ADORA2A (0.39) | ALDH1A1ADORA2AADORA2BMEN1KMT2A | |
| SCHEMBL12471410 | 0.69 | ERCC1 (0.54) | TP53ADORA2B | |
| SCHEMBL15427289 | 0.69 | CNR2 (0.48) | THRATHRBTSHRCNR2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7718781-B2 | Hydroxypyridonate and hydroxypyrimidinone chelating agents | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-05-18 | — | — | US | disclosed |