Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 12/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13367434 | 0.88 | LCK (0.43) | LCKCA12CA1CA9PI4KB | |
| SCHEMBL13339668 | 0.88 | LCK (0.47) | LCKCA12CA1CA9 | |
| SCHEMBL3492278 | 0.86 | LCK (0.42) | LCKCA12CA1CA9PI4KB | |
| SCHEMBL13367440 | 0.81 | IKBKB (0.41) | LCKCA12CA1CA9 | |
| SCHEMBL13367308 | 0.74 | METAP1 (0.46) | LCKCA12CA1CA9 | |
| SCHEMBL13402237 | 0.73 | ALDH1A1 (0.49) | LCK | |
| SCHEMBL22621090 | 0.72 | LCK (0.46) | LCKCA12CA1CA9 | |
| SCHEMBL3494803 | 0.72 | ALDH1A1 (0.47) | LCK | |
| SCHEMBL13339649 | 0.71 | LCK (0.40) | LCKCA12CA1CA9 | |
| SCHEMBL13367311 | 0.71 | IKBKB (0.39) | LCKCA12CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100113418-A1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-05-06 | — | — | US | disclosed |
| US-20100093777-A1 | SPIRO-RING COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100093777-A1 | SPIRO-RING COMPOUND | ACACA, PC, ACACB | LCK 3605/4885CA12 3761/4885CA1 3518/4885 |
| US-20100113418-A1 | HETEROCYCLIC COMPOUND | ACACA, ACAT1, CPT1B | LCK 3484/4885CA12 4155/4885CA1 4041/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.