SCHEMBL13367483

SCHEMBL13367483

Cc1ccc(N(C)c2ccccc2-c2cccc3ccccc23)cc1

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 2/20 0.41
CES1 P23141 1/20 0.41
MAOA P21397 1/20 0.40
MAOB P27338 1/20 0.40
DHFR P00374 2/20 0.37
CYP2A6 P11509 2/20 0.37
ALDH1A1 P00352 2/20 0.37
KDM4E B2RXH2 1/20 0.37
CYP1A2 P05177 2/20 0.37
HTR1A P08908 2/20 0.37
HTR7 P34969 2/20 0.37
C5AR1 P21730 1/20 0.37
TDP1 Q9NUW8 1/20 0.36
HTR2C P28335 1/20 0.36
TSHR P16473 1/20 0.35
CRHR1 P34998 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C19 P33261 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12048738 0.86 SIGMAR1 (0.50) SIGMAR1CES1DHFRCYP2A6ALDH1A1
SCHEMBL13367492 0.86 SIGMAR1 (0.40) SIGMAR1MAOAMAOBDHFRCYP2A6
SCHEMBL27380432 0.86 SLC6A9 (0.42) SIGMAR1DHFRALDH1A1KDM4ETDP1
SCHEMBL13367489 0.83 SIGMAR1 (0.45) SIGMAR1DHFRHTR1AHTR7CYP2D6
SCHEMBL13367365 0.83 MCL1 (0.41) SIGMAR1DHFRKDM4EHTR1AHTR7
SCHEMBL12048245 0.82 SIGMAR1 (0.46) SIGMAR1CES1DHFRCYP2A6ALDH1A1
SCHEMBL13338539 0.80 MAOA (0.38) SIGMAR1CES1MAOAMAOBDHFR
SCHEMBL12048255 0.79 SIGMAR1 (0.47) SIGMAR1DHFRCYP2A6ALDH1A1CYP1A2
SCHEMBL12047918 0.79 SIGMAR1 (0.46) SIGMAR1CES1DHFRCYP2A6ALDH1A1
SCHEMBL5223360 0.77 SIGMAR1 (0.50) SIGMAR1CYP2A6ALDH1A1KDM4ECYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100108997-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-05-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100108997-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same OR10J3, OCIAD1, OCIAD2 SIGMAR1 699/4885CES1 3014/4885MAOA 1402/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.