SCHEMBL13367486

SCHEMBL13367486

Cc1ccccc1N(C)c1ccc(C(C)(C)C)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.40
MEN1 O00255 1/20 0.37
RAB9A P51151 1/20 0.37
KMT2A Q03164 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
KDM4C Q9H3R0 1/20 0.37
LMNA P02545 2/20 0.34
TYR P14679 1/20 0.34
SIGMAR1 Q99720 2/20 0.33
HSD11B1 P28845 2/20 0.33
MAPK13 O15264 1/20 0.33
MAPK12 P53778 1/20 0.33
MAPK11 Q15759 1/20 0.33
MAPK14 Q16539 1/20 0.33
ALDH1A1 P00352 1/20 0.33
HSD17B10 Q99714 1/20 0.33
TP53 P04637 1/20 0.33
THRB P10828 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
GPBAR1 Q8TDU6 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12597656 0.83 KDM4C (0.45) TSHRMEN1RAB9AKMT2ANPSR1
SCHEMBL21173573 0.83 TSHR (0.41) TSHRMEN1RAB9AKMT2ANPSR1
SCHEMBL13367414 0.80 TSHR (0.46) TSHRNPSR1LMNASIGMAR1MAPK13
SCHEMBL21740838 0.80 TSHR (0.39) TSHRMEN1RAB9AKMT2ANPSR1
SCHEMBL20650050 0.80 TSHR (0.39) TSHRMEN1RAB9AKMT2ANPSR1
SCHEMBL20384981 0.80 TSHR (0.41) TSHRMEN1KMT2ASIGMAR1ACHE
SCHEMBL2198610 0.80 TSHR (0.41) TSHRMEN1KMT2ASIGMAR1ACHE
SCHEMBL10296037 0.79 TSHR (0.41) TSHRMEN1RAB9AKMT2ANPSR1
SCHEMBL20210345 0.79 TSHR (0.47) TSHRRAB9AKDM4CLMNATYR
SCHEMBL14466519 0.79 RAB9A (0.42) TSHRMEN1RAB9AKMT2ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11584753-B2 Bisbenzofuran-fused 2,8-diaminoindeno[1,2-b]fluorene derivatives and related compounds as materials for organic electroluminescent devices (OLED) MERCK PATENT GMBH (DE) 2023-02-21 US disclosed
EP-3564249-B1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING SAME LG CHEMICAL LTD (KR) 2021-01-20 EP disclosed
EP-3544984-B1 BISBENZOFURAN-FUSED 2,8-DIAMINOINDENO[1,2-B]FLUORENE DERIVATIVES AND RELATED COMPOUNDS AS MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES (OLED) MERCK PATENT GMBH (DE) 2020-12-23 EP disclosed
WO-2020159279-A1 POLYCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME 주식회사 엘지화학 2020-08-06 WO disclosed
US-10651411-B2 Compound and organic light emitting device containing same LG CHEM, LTD. (KR) 2020-05-12 US disclosed
EP-3564249-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING SAME LG Chem, Ltd. (KR) 2019-11-06 EP disclosed
US-20190315764-A1 BISBENZOFURAN-FUSED 2,8-DIAMINOINDENO[1,2-B]FLUORENE DERIVATIVES AND RELATED COMPOUNDS AS MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES (OLED) MERCK PATENT GMBH (DE) 2019-10-17 US disclosed
WO-2018095888-A1 BISBENZOFURAN-FUSED 2,8-DIAMINOINDENO[1,2-B]FLUORENE DERIVATIVES AND RELATED COMPOUNDS AS MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES (OLED) MERCK PATENT GMBH (DE) 2018-05-31 WO disclosed
US-20180145272-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE CONTAINING SAME LG CHEM, LTD. (KR) 2018-05-24 US disclosed
US-20180145272-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE CONTAINING SAME LG CHEM, LTD. (KR) 2018-05-24 US disclosed
US-20100108997-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-05-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180145272-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE CONTAINING SAME CRY1, CRY2, OR10J3 TSHR 3775/4885MEN1 801/4885RAB9A 3113/4885
US-10651411-B2 Compound and organic light emitting device containing same CRY1, CRY2, OR10J3 TSHR 3775/4885MEN1 801/4885RAB9A 3113/4885
US-20190315764-A1 BISBENZOFURAN-FUSED 2,8-DIAMINOINDENO[1,2-B]FLUORENE DERIVATIVES AND RELATED COMPOUNDS AS MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES (OLED) OCIAD1, OCIAD2, AOC1 TSHR 4385/4885MEN1 2637/4885RAB9A 1290/4885
US-20100108997-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same OR10J3, OCIAD1, OCIAD2 TSHR 3278/4885MEN1 3828/4885RAB9A 1308/4885
US-11584753-B2 Bisbenzofuran-fused 2,8-diaminoindeno[1,2-b]fluorene derivatives and related compounds as materials for organic electroluminescent devices (OLED) OCIAD1, OCIAD2, AOC1 TSHR 4385/4885MEN1 2637/4885RAB9A 1290/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.