SCHEMBL13367671

SCHEMBL13367671

CSc1ccc(N(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.50
CYP1A2 P05177 2/20 0.50
CYP3A4 P08684 2/20 0.50
CYP2C9 P11712 2/20 0.50
CYP2C19 P33261 2/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
KDM4E B2RXH2 1/20 0.50
CYP2D6 P10635 1/20 0.50
MAPT P10636 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
EGFR P00533 1/20 0.44
PDGFRB P09619 1/20 0.44
KDR P35968 1/20 0.44
KMT2A Q03164 4/20 0.42
MEN1 O00255 3/20 0.42
PTGS2 P35354 2/20 0.42
CRHBP P24387 1/20 0.42
ATM Q13315 1/20 0.42
CRHR2 Q13324 1/20 0.42
TLR9 Q9NR96 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21173484 1.00 ALDH1A1 (0.50) ALDH1A1CYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL12533929 0.94 PTGS2 (0.47) ALDH1A1CYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL21236832 0.90 ALDH1A1 (0.42) ALDH1A1CYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL19687714 0.88 EGFR (0.41) ALDH1A1CYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL8943689 0.87 CYP1A2 (0.53) ALDH1A1CYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL13367669 0.85 EGFR (0.39) ALDH1A1CYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL25059094 0.84 EGFR (0.54) ALDH1A1CYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL12533890 0.83 NISCH (0.42) ALDH1A1PTGS2SLC6A4NOX1
SCHEMBL12683362 0.82 CYP1A1 (0.49) ALDH1A1CYP1A2L3MBTL1KDM4ETDP1
SCHEMBL21183244 0.81 MEN1 (0.46) ALDH1A1MAPTTDP1EGFRPDGFRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10472373-B2 Thienothiophene/dithienothiophene-triphenylamine/tetraphenylethylene derivatives for organic light emitting diodes TUBITAK (TR) 2019-11-12 US disclosed
US-10461201-B2 Highly-fluorescent and photo-stable chromophores for wavelength conversion NITTO DENKO CORPORATION (JP) 2019-10-29 US disclosed
US-20100108997-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-05-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100108997-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same OR10J3, OCIAD1, OCIAD2 ALDH1A1 428/4885CYP1A2 1021/4885CYP3A4 942/4885
US-10472373-B2 Thienothiophene/dithienothiophene-triphenylamine/tetraphenylethylene derivatives for organic light emitting diodes TST, OCIAD1, TPT1 ALDH1A1 675/4885CYP1A2 1816/4885CYP3A4 680/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.