Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL9 | O00512 | 1/20 | 0.50 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.50 |
| ▸ | FBP1 | P09467 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | BRAF | P15056 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6367735 | 0.91 | ALOX5 (0.47) | BCL9CTNNB1FBP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6915911 | 0.91 | FBP1 (0.53) | FBP1ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL11798840 | 0.90 | ALDH1A1 (0.50) | BCL9CTNNB1FBP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL275826 | 0.88 | ALDH1A1 (0.50) | FBP1ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL275825 | 0.88 | ALDH1A1 (0.50) | FBP1ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL7820823 | 0.88 | ALDH1A1 (0.50) | FBP1ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL11327350 | 0.83 | GLO1 (0.58) | FBP1ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL11327355 | 0.83 | GLO1 (0.58) | FBP1ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL29024906 | 0.82 | POLB (0.43) | FBP1ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL15434532 | 0.81 | FBP1 (0.53) | BCL9CTNNB1FBP1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2514745-A1 | GPR120 receptor agonists and uses thereof | Metabolex Inc. (US) | 2012-10-24 | — | — | EP | disclosed |