Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABBR1 | Q9UBS5 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24549452 | 0.78 | GABRR1 (0.32) | GABBR1 | |
| SCHEMBL24549459 | 0.78 | GABRR1 (0.32) | GABBR1 | |
| SCHEMBL21205920 | 0.78 | GABRR1 (0.32) | GABBR1 | |
| SCHEMBL12186297 | 0.76 | — | — | |
| SCHEMBL13660349 | 0.74 | CCR2 (0.30) | — | |
| SCHEMBL20810121 | 0.74 | CCR2 (0.30) | — | |
| SCHEMBL17181427 | 0.74 | — | — | |
| SCHEMBL13985486 | 0.72 | LMNA (0.41) | — | |
| SCHEMBL9294943 | 0.71 | — | — | |
| SCHEMBL20095927 | 0.71 | SLC6A4 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2014285-B1 | NPYY5 antagonists | SHIONOGI & CO (JP) | 2010-05-05 | — | — | EP | disclosed |
| EP-1249233-B9 | NPYY5 ANTAGONISTS | SHIONOGI & CO (JP) | 2009-08-05 | — | — | EP | disclosed |
| EP-1249233-B1 | NPYY5 ANTAGONISTS | SHIONOGI & CO (JP) | 2008-08-20 | — | — | EP | disclosed |