Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 19/20 | 0.47 |
| ▸ | NOS3 | P29474 | 17/20 | 0.47 |
| ▸ | NOS2 | P35228 | 17/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3784565 | 0.62 | ENPP2 (0.44) | KDM4EALDH1A1ENPP2 | |
| SCHEMBL12928903 | 0.62 | NOS3 (0.50) | NOS1NOS3NOS2KDM4EALDH1A1 | |
| SCHEMBL6642652 | 0.62 | NOS1 (0.63) | NOS1NOS3NOS2 | |
| SCHEMBL6646529 | 0.61 | NOS1 (0.67) | NOS1NOS3NOS2 | |
| SCHEMBL6644288 | 0.61 | NOS1 (0.79) | NOS1NOS3NOS2 | |
| SCHEMBL3787449 | 0.60 | ENPP2 (0.41) | KDM4EALDH1A1ENPP2 | |
| SCHEMBL3791170 | 0.60 | ENPP2 (0.41) | NOS1NOS3NOS2KDM4EALDH1A1 | |
| SCHEMBL14752221 | 0.60 | ENPP2 (0.38) | KDM4EALDH1A1ENPP2 | |
| SCHEMBL3786309 | 0.59 | ENPP2 (0.40) | KDM4EALDH1A1ENPP2 | |
| SCHEMBL3790291 | 0.59 | ENPP2 (0.40) | KDM4EALDH1A1ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010051043-A1 | BENZOXAZOLE KINASE INHIBITORS AND METHODS OF USE | INTELLIKINE, INC. (US) | 2010-05-06 | — | — | WO | disclosed |