SCHEMBL13370901

SCHEMBL13370901

COCc1cnc(C(=O)O)c(C(=O)OC)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.39
ALDH1A1 P00352 2/20 0.39
HPGD P15428 2/20 0.39
MAPT P10636 2/20 0.39
GAA P10253 1/20 0.39
ALOX15 P16050 1/20 0.39
TSHR P16473 1/20 0.39
HSD17B10 Q99714 1/20 0.39
L3MBTL1 Q9Y468 2/20 0.36
MAPK1 P28482 1/20 0.36
HCAR2 Q8TDS4 1/20 0.36
ASPH Q12797 1/20 0.36
KDM8 Q8N371 1/20 0.36
CA12 O43570 2/20 0.36
CA1 P00915 2/20 0.36
CA2 P00918 2/20 0.36
CA7 P43166 2/20 0.36
CA9 Q16790 2/20 0.36
CA14 Q9ULX7 2/20 0.36
PDK2 Q15119 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31220981 0.91 KDM4E (0.41) KDM4EALDH1A1HPGDMAPTGAA
SCHEMBL2389957 0.91 KDM4E (0.41) KDM4EALDH1A1HPGDMAPTGAA
SCHEMBL2338977 0.89 KDM5A (0.40) KDM4EALDH1A1MAPTALOX15TSHR
SCHEMBL8758676 0.88 KDM5A (0.38) KDM4EALDH1A1HPGDMAPTGAA
SCHEMBL29619773 0.88 KDM5A (0.38) KDM4EALDH1A1HPGDMAPTGAA
SCHEMBL28574787 0.87 KDM4E (0.43) KDM4EALDH1A1HPGDMAPTTSHR
SCHEMBL29280504 0.85 CYP4F2 (0.44) KDM4EALDH1A1HPGDMAPTGAA
Nitric Acid SCHEMBL7052214 0.81 PKM (0.37) KDM4EALDH1A1MAPTALOX15TSHR
SCHEMBL13363453 0.79 LMNA (0.38) KDM4EALDH1A1L3MBTL1HCAR2ASPH
SCHEMBL29619790 0.78 GABRA1 (0.44) KDM4EALDH1A1HPGDMAPTCA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010055139-A1 PROCESS FOR MANUFACTURING SUBSTITUTED 3-PYRIDYLMETHYL AMMONIUM BROMIDES BASF SE (DE) 2010-05-20 WO disclosed