SCHEMBL13373971

SCHEMBL13373971

Cc1nnc(-c2ccc(N=Nc3c(O)ccc4ccccc34)cc2)o1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 9/20 0.58
▸ L3MBTL1 Q9Y468 6/20 0.58
▸ KMT2A Q03164 6/20 0.58
▸ TDP1 Q9NUW8 5/20 0.58
▸ MEN1 O00255 5/20 0.58
▸ HSP90AA1 P07900 3/20 0.58
▸ LMNA P02545 3/20 0.58
▸ GAA P10253 2/20 0.58
▸ ALPL P05186 1/20 0.58
▸ ALPI P09923 1/20 0.58
▸ ALPG P10696 1/20 0.58
▸ CASP3 P42574 1/20 0.58
▸ RECQL P46063 1/20 0.58
▸ MMP14 P50281 1/20 0.58
▸ SENP8 Q96LD8 1/20 0.58
▸ SENP7 Q9BQF6 1/20 0.58
▸ SENP6 Q9GZR1 1/20 0.58
▸ THRB P10828 5/20 0.57
▸ MAPK1 P28482 4/20 0.55
▸ GLO1 Q04760 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12677660 0.91 MAPT (0.65) MAPTL3MBTL1KMT2ATDP1MEN1
SCHEMBL10259399 0.84 THRB (0.58) MAPTL3MBTL1KMT2ATDP1MEN1
SCHEMBL13884065 0.83 MAPT (0.49) MAPTL3MBTL1KMT2ATDP1MEN1
SCHEMBL7614146 0.80 MAPT (0.81) MAPTL3MBTL1KMT2ATDP1MEN1
SCHEMBL7614142 0.80 MAPT (0.81) MAPTL3MBTL1KMT2ATDP1MEN1
SCHEMBL3705373 0.79 MAPT (0.90) MAPTL3MBTL1KMT2ATDP1MEN1
SCHEMBL3705371 0.79 MAPT (0.90) MAPTL3MBTL1KMT2ATDP1MEN1
SCHEMBL3705370 0.79 MAPT (0.90) MAPTL3MBTL1KMT2ATDP1MEN1
SCHEMBL11143645 0.78 MAPT (0.77) MAPTL3MBTL1KMT2ATDP1MEN1
SCHEMBL4751325 0.78 MAPT (0.77) MAPTL3MBTL1KMT2ATDP1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8309696-B2 AZO pigment, electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2012-11-13 — — US disclosed
US-8288066-B2 Electroconductive support with a photosensitive layer of an arylamine-based compound; high sensitivity, chargeability, residual potential, light resistance MITSUBISHI CHEMICAL CORPORATION (JP) 2012-10-16 — — US disclosed
US-20100075239-A1 AZO PIGMENT, ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2010-03-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100075239-A1 AZO PIGMENT, ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CRY1, IK, APC MAPT 2989/4885L3MBTL1 4811/4885KMT2A 2223/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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