Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBFB | Q13951 | 6/20 | 0.43 |
| ▸ | ATR | Q13535 | 1/20 | 0.35 |
| ▸ | NT5E | P21589 | 1/20 | 0.35 |
| ▸ | ILK | Q13418 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | TYMS | P04818 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13375186 | 0.90 | FGFR1 (0.39) | CBFBATRNT5EALDH1A1HPGD | |
| SCHEMBL6283876 | 0.88 | NT5E (0.35) | CBFBNT5EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL12027128 | 0.88 | PKM (0.38) | CBFBNT5EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL13375193 | 0.80 | CHEK1 (0.38) | ATRALDH1A1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL13375032 | 0.80 | CBFB (0.40) | CBFBALDH1A1SMN1; SMN2MAPTNPC1 | |
| SCHEMBL10240066 | 0.80 | FGFR1 (0.41) | ILKALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL28500913 | 0.80 | RAB9A (0.45) | CBFBATRALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL30061152 | 0.80 | SMN1; SMN2 (0.38) | CBFBALDH1A1HPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL30061331 | 0.80 | RAB9A (0.45) | CBFBATRALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL28498751 | 0.80 | SMN1; SMN2 (0.38) | CBFBALDH1A1HPGDSMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8288425-B2 | Benzimidazoles | AVENTIS PHARMACEUTICALS INC. (US) | 2012-10-16 | — | — | US | disclosed |