Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.45 |
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | NPC1 | O15118 | 7/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | GAA | P10253 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 6/20 | 0.41 |
| ▸ | PKM | P14618 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.39 |
| ▸ | RELA | Q04206 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28500913 | 1.00 | RAB9A (0.45) | RAB9AMAPTALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL5952765 | 0.83 | NPC1 (0.48) | RAB9AMAPTALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL5951395 | 0.83 | ALDH1A1 (0.40) | RAB9AMAPTALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL28498751 | 0.83 | SMN1; SMN2 (0.38) | RAB9AMAPTALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL30061152 | 0.83 | SMN1; SMN2 (0.38) | RAB9AMAPTALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL5952198 | 0.82 | FABP6 (0.51) | RAB9AMAPTNPC1KDM4EMEN1 | |
| SCHEMBL28496270 | 0.82 | FGFR1 (0.46) | ALDH1A1HPGDMETAP2FGFR1KDR | |
| SCHEMBL30059191 | 0.82 | APAF1 (0.40) | RAB9AMAPTALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL30061285 | 0.82 | FGFR1 (0.46) | ALDH1A1HPGDMETAP2FGFR1KDR | |
| SCHEMBL6283876 | 0.81 | NT5E (0.35) | RAB9AMAPTALDH1A1NPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112047932-B | Pyrazole spleen tyrosine kinase inhibitor and preparation method and application thereof | 中国药科大学 | 2022-11-08 | — | — | CN | disclosed |