Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.33 |
| ▸ | HPGD | P15428 | 7/20 | 0.33 |
| ▸ | MAPT | P10636 | 6/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.33 |
| ▸ | NPC1 | O15118 | 6/20 | 0.33 |
| ▸ | RAB9A | P51151 | 6/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 2/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.32 |
| ▸ | RELA | Q04206 | 2/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12027128 | 0.89 | PKM (0.38) | NT5EALDH1A1SMN1; SMN2HPGDMAPT | |
| SCHEMBL13375019 | 0.88 | CBFB (0.43) | NT5EALDH1A1SMN1; SMN2HPGDMAPT | |
| SCHEMBL13375186 | 0.86 | FGFR1 (0.39) | NT5EALDH1A1SMN1; SMN2HPGDMAPT | |
| SCHEMBL5951395 | 0.83 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2HPGDMAPTKDM4E | |
| SCHEMBL10240066 | 0.81 | FGFR1 (0.41) | ALDH1A1HPGDKDM4EHSD17B10FGFR1 | |
| SCHEMBL30061152 | 0.81 | SMN1; SMN2 (0.38) | ALDH1A1SMN1; SMN2HPGDMAPTKDM4E | |
| SCHEMBL30061331 | 0.81 | RAB9A (0.45) | ALDH1A1SMN1; SMN2HPGDMAPTKDM4E | |
| SCHEMBL28500913 | 0.81 | RAB9A (0.45) | ALDH1A1SMN1; SMN2HPGDMAPTKDM4E | |
| SCHEMBL28498751 | 0.81 | SMN1; SMN2 (0.38) | ALDH1A1SMN1; SMN2HPGDMAPTKDM4E | |
| SCHEMBL28498762 | 0.79 | FGFR1 (0.54) | FGFR1FLT1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6897208-B2 | Benzimidazoles | AVENTIS PHARMACEUTICALS INC. (US) | 2005-05-24 | — | — | US | disclosed |