Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | TUBB4A | P04350 | 8/20 | 0.57 |
| ▸ | TUBB | P07437 | 8/20 | 0.57 |
| ▸ | TUBA3C | P0DPH7 | 8/20 | 0.57 |
| ▸ | TUBA1B | P68363 | 8/20 | 0.57 |
| ▸ | TUBA4A | P68366 | 8/20 | 0.57 |
| ▸ | TUBB4B | P68371 | 8/20 | 0.57 |
| ▸ | TUBB3 | Q13509 | 8/20 | 0.57 |
| ▸ | TUBB2A | Q13885 | 8/20 | 0.57 |
| ▸ | TUBB8 | Q3ZCM7 | 8/20 | 0.57 |
| ▸ | TUBA3E | Q6PEY2 | 8/20 | 0.57 |
| ▸ | TUBA1A | Q71U36 | 8/20 | 0.57 |
| ▸ | TUBA1C | Q9BQE3 | 8/20 | 0.57 |
| ▸ | TUBB6 | Q9BUF5 | 8/20 | 0.57 |
| ▸ | TUBB2B | Q9BVA1 | 8/20 | 0.57 |
| ▸ | TUBB1 | Q9H4B7 | 8/20 | 0.57 |
| ▸ | SYK | P43405 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1336449 | 0.91 | SMN1; SMN2 (0.57) | SMN1; SMN2HSD17B10L3MBTL1TUBB4ATUBB | |
| SCHEMBL12130384 | 0.83 | SMN1; SMN2 (0.47) | SMN1; SMN2HSD17B10L3MBTL1TUBB4ATUBB | |
| SCHEMBL1336724 | 0.81 | MEN1 (0.65) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL6103129 | 0.80 | TUBB4A (0.64) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL1337756 | 0.80 | TUBB4A (0.54) | SMN1; SMN2HSD17B10L3MBTL1TUBB4ATUBB | |
| SCHEMBL27719184 | 0.77 | NSD2 (0.58) | SMN1; SMN2L3MBTL1KDM4EMAPTMEN1 | |
| SCHEMBL7374498 | 0.76 | GCGR (0.59) | SMN1; SMN2HSD17B10L3MBTL1KDM4EMAPT | |
| SCHEMBL1337935 | 0.75 | TUBB4A (0.55) | SMN1; SMN2HSD17B10L3MBTL1TUBB4ATUBB | |
| SCHEMBL1336755 | 0.75 | ALOX15 (0.60) | SMN1; SMN2HSD17B10L3MBTL1TUBB4ATUBB | |
| SCHEMBL12130376 | 0.75 | ALDH1A1 (0.45) | SMN1; SMN2HSD17B10L3MBTL1TUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110275643-A1 | AROYLQUINOLINE COMPOUNDS | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2011-11-10 | — | — | US | disclosed |
| US-20110275643-A1 | AROYLQUINOLINE COMPOUNDS | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2011-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110275643-A1 | AROYLQUINOLINE COMPOUNDS | TUBA1C, TUBB1, TUBB3 | SMN1; SMN2 1630/4885HSD17B10 3886/4885L3MBTL1 2707/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.