Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 2/20 | 0.55 |
| ▸ | ALAD | P13716 | 2/20 | 0.54 |
| ▸ | DHODH | Q02127 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.47 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | KMO | O15229 | 2/20 | 0.44 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.44 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.44 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.43 |
| ▸ | MMP12 | P39900 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 2/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | CTSA | P10619 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1761887 | 0.86 | ALAD (0.59) | DAOALADHDAC6KMOHSD17B1 | |
| SCHEMBL27316069 | 0.83 | HSD17B1 (0.53) | HDAC6HSD17B10HSD17B1HSD17B2CNR1 | |
| SCHEMBL6869311 | 0.82 | DAO (0.62) | DAOALADHDAC6MMP12CNR2 | |
| SCHEMBL505511 | 0.82 | ALAD (0.70) | DAOALADHDAC6KMOMMP12 | |
| SCHEMBL3641638 | 0.81 | HSD17B1 (0.59) | DAOALADHDAC6HSD17B1HSD17B2 | |
| SCHEMBL1800477 | 0.81 | ALAD (0.69) | DAOALADDHODHHDAC6AKR1C2 | |
| SCHEMBL6451881 | 0.80 | ALAD (0.68) | DAOALADHDAC6HSD17B1HSD17B2 | |
| SCHEMBL5718246 | 0.79 | CTSA (0.42) | DHODHHDAC6AKR1C2AKR1C1HSD17B10 | |
| SCHEMBL5718227 | 0.78 | MAPT (0.40) | DHODHHDAC6AKR1C2AKR1C1HSD17B10 | |
| SCHEMBL3638317 | 0.78 | ALAD (0.51) | ALADDHODHHDAC6KMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2177518-A1 | Organic compounds | Novartis AG (CH) | 2010-04-21 | — | — | EP | disclosed |