Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HSD17B1 | P14061 | 5/20 | 0.38 |
| ▸ | HSD17B2 | P37059 | 5/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CTSA | P10619 | 1/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | LDHA | P00338 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13376205 | 0.78 | DAO (0.55) | MAPTHSD17B1HSD17B2HDAC6CNR1 | |
| SCHEMBL5718246 | 0.77 | CTSA (0.42) | MAPTALDH1A1HSD17B1HSD17B2HDAC6 | |
| SCHEMBL27316069 | 0.74 | HSD17B1 (0.53) | HSD17B1HSD17B2HDAC6CNR1CNR2 | |
| SCHEMBL13044160 | 0.67 | HDAC6 (0.57) | HSD17B1HSD17B2HDAC6CNR1MMP12 | |
| SCHEMBL20288135 | 0.67 | HPGD (0.48) | ALDH1A1HSD17B1HSD17B2CNR1HSD17B10 | |
| SCHEMBL30916744 | 0.67 | MAPT (0.53) | MAPTALDH1A1CNR1CNR2HSD17B10 | |
| SCHEMBL14944580 | 0.65 | HDAC6 (0.58) | HDAC6MMP12 | |
| SCHEMBL2319480 | 0.65 | PGR (0.46) | MAPTALDH1A1CNR1CNR2HSD17B10 | |
| SCHEMBL17715729 | 0.65 | AKR1C2 (0.40) | MAPTALDH1A1HSD17B1HSD17B2CNR1 | |
| SCHEMBL23773782 | 0.65 | ALDH1A1 (0.43) | ALDH1A1HSD17B1HSD17B2HSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7141637-B2 | Metallocene compounds and process for the preparation of propylene polymers | BASELL POLYOLEFINE GMBH (DE) | 2006-11-28 | — | — | US | disclosed |
| EP-1448578-B1 | METALLOCENE COMPOUNDS AND PROCESS FOR THE PREPARATION OF PROPYLENE POLYMERS | BASELL POLYOLEFINE GMBH (DE) | 2006-07-26 | — | — | EP | disclosed |
| US-20050010058-A1 | Such as {Dimethyl-silyl-(5-isopropyl-2-methyl-3-phenyl-cyclopento[2,3-b]thiophen-6-yl)-(2-methyl-4-phenyl-[3a,4-dihydro]azulen-1-yl)}ZrCl2 catalyst for homo or copolymerization of propylene | EXXONMOBIL CHEMICAL PATENTS INC. | 2005-01-13 | — | — | US | disclosed |
| EP-1448578-A1 | METALLOCENE COMPOUNDS AND PROCESS FOR THE PREPARATION OF PROPYLENE POLYMERS | Basell Polyolefine GmbH (DE) | 2004-08-25 | — | — | EP | disclosed |
| WO-2003045964-A1 | METALLOCENE COMPOUNDS AND PROCESS FOR THE PREPARATION OF PROPYLENE POLYMERS | BASELL POLYOLEFINE GMBH (DE) | 2003-06-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050010058-A1 | Such as {Dimethyl-silyl-(5-isopropyl-2-methyl-3-phenyl-cyclopento[2,3-b]thiophen-6-yl)-(2-methyl-4-phenyl-[3a,4-dihydro]azulen-1-yl)}ZrCl2 catalyst for homo or copolymerization of propylene | CHRM1, YWHAZ, PYM1 | MAPT 4468/4885ALDH1A1 2017/4885HSD17B1 1811/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.