Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 1/20 | 0.42 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ICMT | O60725 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13376205 | 0.79 | DAO (0.55) | CTSAHSD17B1HSD17B2MAPTMMP12 | |
| SCHEMBL5718227 | 0.77 | MAPT (0.40) | CTSAHSD17B1HSD17B2ALDH1A1MAPT | |
| SCHEMBL27316069 | 0.75 | HSD17B1 (0.53) | HSD17B1HSD17B2HDAC6HPGDSMN1; SMN2 | |
| SCHEMBL12960171 | 0.71 | PARP1 (0.53) | ALDH1A1MAPTHDAC6HPGDSMN1; SMN2 | |
| SCHEMBL6563992 | 0.70 | HSD17B1 (0.60) | HSD17B1HSD17B2HDAC6 | |
| SCHEMBL27688659 | 0.68 | HDAC6 (0.57) | HSD17B1HSD17B2ALDH1A1MAPTMMP12 | |
| M-Xylene SCHEMBL11058726 | 0.68 | ACHE (0.56) | HDAC6HPGDSMN1; SMN2HSD17B10LMNA | |
| SCHEMBL20288135 | 0.68 | HPGD (0.48) | HSD17B1HSD17B2ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL30916744 | 0.68 | MAPT (0.53) | ALDH1A1MAPTHPGDCNR1CNR2 | |
| SCHEMBL2319480 | 0.66 | PGR (0.46) | ALDH1A1MAPTCNR1CNR2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7141637-B2 | Metallocene compounds and process for the preparation of propylene polymers | BASELL POLYOLEFINE GMBH (DE) | 2006-11-28 | — | — | US | disclosed |
| EP-1448578-B1 | METALLOCENE COMPOUNDS AND PROCESS FOR THE PREPARATION OF PROPYLENE POLYMERS | BASELL POLYOLEFINE GMBH (DE) | 2006-07-26 | — | — | EP | disclosed |
| US-20050010058-A1 | Such as {Dimethyl-silyl-(5-isopropyl-2-methyl-3-phenyl-cyclopento[2,3-b]thiophen-6-yl)-(2-methyl-4-phenyl-[3a,4-dihydro]azulen-1-yl)}ZrCl2 catalyst for homo or copolymerization of propylene | EXXONMOBIL CHEMICAL PATENTS INC. | 2005-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050010058-A1 | Such as {Dimethyl-silyl-(5-isopropyl-2-methyl-3-phenyl-cyclopento[2,3-b]thiophen-6-yl)-(2-methyl-4-phenyl-[3a,4-dihydro]azulen-1-yl)}ZrCl2 catalyst for homo or copolymerization of propylene | CHRM1, YWHAZ, PYM1 | CTSA 4085/4885HSD17B1 1811/4885HSD17B2 2074/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.