Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | PHGDH | O43175 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CRHBP | P24387 | 1/20 | 0.31 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24342473 | 1.00 | KMT2A (0.34) | KMT2AMEN1LMNAL3MBTL1NPSR1 | |
| SCHEMBL11168711 | 0.84 | MEN1 (0.40) | KMT2AMEN1LMNAL3MBTL1NPSR1 | |
| SCHEMBL21795024 | 0.81 | LMNA (0.31) | KMT2AMEN1LMNAL3MBTL1 | |
| SCHEMBL26321192 | 0.81 | ALDH1A1 (0.33) | KMT2AMEN1LMNAL3MBTL1NPSR1 | |
| SCHEMBL18745271 | 0.78 | NPSR1 (0.48) | KMT2AMEN1LMNAL3MBTL1NPSR1 | |
| SCHEMBL20662979 | 0.78 | MEN1 (0.33) | KMT2AMEN1NPSR1ALDH1A1FAAH | |
| SCHEMBL12334814 | 0.77 | CRHBP (0.46) | KMT2AMEN1L3MBTL1NPSR1ALDH1A1 | |
| SCHEMBL25633940 | 0.75 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL28449517 | 0.72 | RAB9A (0.44) | KMT2AMEN1LMNAL3MBTL1NPSR1 | |
| SCHEMBL10908275 | 0.72 | ALDH1A1 (0.55) | KMT2AMEN1LMNANPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3552664-A1 | PROTEOSTASIS REGULATORS | Proteostasis Therapeutics, Inc. (US) | 2019-10-16 | — | — | EP | disclosed |
| EP-1832928-B1 | Planographic printing plate precursor, and stacks of the same | FUJIFILM CORP (JP) | 2010-04-28 | — | — | EP | disclosed |