SCHEMBL13378285

SCHEMBL13378285

CC(C)C(CC(C)(C)C)c1ccc(O)c(O)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 9/20 0.50
TDP1 Q9NUW8 8/20 0.50
MAPT P10636 7/20 0.50
RECQL P46063 6/20 0.50
HSD17B10 Q99714 5/20 0.50
LMNA P02545 4/20 0.50
MTOR P42345 4/20 0.50
HIF1A Q16665 4/20 0.50
KMT2A Q03164 4/20 0.50
ALOX15 P16050 4/20 0.50
NFKB1 P19838 3/20 0.50
TSHR P16473 3/20 0.50
POLB P06746 3/20 0.50
BLM P54132 3/20 0.50
THPO P40225 2/20 0.50
APEX1 P27695 1/20 0.50
SHBG P04278 1/20 0.49
ADRB2 P07550 4/20 0.45
PTGS2 P35354 2/20 0.45
OPRK1 P41145 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22276929 0.88 TDP1 (0.46) KDM4ETDP1MAPTRECQLHSD17B10
SCHEMBL14220806 0.86 ESR1 (0.44) KDM4ETDP1MAPTRECQLHSD17B10
SCHEMBL14217129 0.82 TSHR (0.54) LMNAALOX15NFKB1TSHRBLM
SCHEMBL22448293 0.81 TDP1 (0.46) KDM4ETDP1MAPTRECQLHSD17B10
SCHEMBL26015539 0.81 SHBG (0.66) KDM4ETDP1MAPTRECQLHSD17B10
SCHEMBL23996875 0.79 MAPT (0.58) KDM4ETDP1MAPTRECQLHSD17B10
SCHEMBL22920988 0.79 MAPT (0.58) KDM4ETDP1MAPTRECQLHSD17B10
SCHEMBL11880606 0.79 TDP1 (0.58) KDM4ETDP1MAPTRECQLHSD17B10
SCHEMBL20000957 0.79 KDM4E (0.52) KDM4ETDP1MAPTRECQLHSD17B10
SCHEMBL903671 0.79 ESR1 (0.54) KDM4ETDP1MAPTLMNAHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1117002-B1 Negative-working resist composition FUJIFILM CORP (JP) 2010-04-14 EP disclosed