Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 10/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.46 |
| ▸ | RECQL | P46063 | 7/20 | 0.46 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | APEX1 | P27695 | 4/20 | 0.46 |
| ▸ | BLM | P54132 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | MTOR | P42345 | 2/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | THPO | P40225 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12522902 | 0.86 | ESR1 (0.44) | TDP1 | |
| SCHEMBL14216872 | 0.84 | TDP1 (0.32) | TDP1KDM4ERECQLMAPTKMT2A | |
| SCHEMBL14111825 | 0.84 | ALOX15 (0.40) | TDP1KDM4ERECQLMAPTKMT2A | |
| SCHEMBL19184383 | 0.84 | SHBG (0.49) | TDP1HSD17B10ALOX15HPGDALDH1A1 | |
| SCHEMBL14216835 | 0.82 | TSHR (0.54) | BLMALOX15TSHRNFKB1ALDH1A1 | |
| SCHEMBL13378285 | 0.81 | KDM4E (0.50) | TDP1KDM4ERECQLMAPTKMT2A | |
| SCHEMBL23996875 | 0.79 | MAPT (0.58) | TDP1KDM4ERECQLMAPTKMT2A | |
| SCHEMBL22920988 | 0.79 | MAPT (0.58) | TDP1KDM4ERECQLMAPTKMT2A | |
| SCHEMBL11960807 | 0.79 | ESR1 (0.44) | TDP1KDM4EMAPTKMT2ABLM | |
| SCHEMBL784711 | 0.79 | ESR1 (0.44) | TDP1KDM4EMAPTKMT2ABLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023068075-A1 | METHOD FOR PRODUCING SEMICONDUCTOR SUBSTRATE AND RESIST UNDERLAYER FILM-FORMING COMPOSITION | JSR株式会社 | 2023-04-27 | — | — | WO | disclosed |
| EP-2490727-B1 | COMPOSITION FOR THE TREATMENT OF A BONE FRACTURE | BIOMEDICAL BONDING AB (SE) | 2020-09-23 | — | — | EP | disclosed |