Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31477299 | 0.88 | KMT2A (0.53) | KMT2ACYP3A4CYP2C19TSHRLMNA | |
| SCHEMBL12069805 | 0.86 | KMT2A (0.47) | KMT2ACYP3A4CYP2C19TSHRLMNA | |
| SCHEMBL15317931 | 0.86 | KMT2A (0.47) | KMT2ACYP3A4CYP2C19TSHRLMNA | |
| SCHEMBL12069021 | 0.86 | KMT2A (0.47) | KMT2ACYP3A4CYP2C19TSHRLMNA | |
| SCHEMBL15639608 | 0.85 | CTSK (0.43) | KMT2AKEAP1NFE2L2LMNAMEN1 | |
| SCHEMBL330450 | 0.85 | LMNA (0.59) | KMT2ACYP3A4CYP2C19TSHRLMNA | |
| SCHEMBL1071825 | 0.85 | LMNA (0.59) | KMT2ACYP3A4CYP2C19TSHRLMNA | |
| SCHEMBL6356699 | 0.85 | LMNA (0.59) | KMT2ACYP3A4CYP2C19TSHRLMNA | |
| SCHEMBL28736218 | 0.85 | LMNA (0.59) | KMT2ACYP3A4CYP2C19TSHRLMNA | |
| SCHEMBL28772271 | 0.84 | KMT2A (0.56) | KMT2ACYP3A4CYP2C19TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100099896-A1 | METHOD OF PREPARING DOCETAXEL AND INTERMEDIATES USED THEREIN | HANMI PHARM. CO. LTD (KR) | 2010-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100099896-A1 | METHOD OF PREPARING DOCETAXEL AND INTERMEDIATES USED THEREIN | MCL1, DPYD, THPO | KMT2A 3620/4885CYP3A4 1663/4885CYP2C19 3277/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.