Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.40 |
| ▸ | ACACA | Q13085 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13380255 | 0.88 | KMT2A (0.55) | KMT2ACYP2C19CYP3A4TSHRMEN1 | |
| SCHEMBL28573250 | 0.86 | HTT (0.44) | KMT2ACYP2C19CYP3A4CYP1A2HSD17B10 | |
| SCHEMBL28573252 | 0.86 | HTT (0.44) | KMT2ACYP2C19CYP3A4CYP1A2HSD17B10 | |
| SCHEMBL1140664 | 0.84 | KMT2A (0.47) | KMT2ACYP2C19CYP3A4CYP1A2HSD17B10 | |
| SCHEMBL8070685 | 0.84 | SRC (0.47) | CYP2C19CYP1A2HSD17B10LMNAALDH1A1 | |
| SCHEMBL7139715 | 0.84 | SRC (0.47) | CYP2C19CYP1A2HSD17B10LMNAALDH1A1 | |
| SCHEMBL330450 | 0.84 | LMNA (0.59) | KMT2ACYP2C19CYP3A4CYP1A2TSHR | |
| SCHEMBL28736218 | 0.84 | LMNA (0.59) | KMT2ACYP2C19CYP3A4CYP1A2TSHR | |
| SCHEMBL6356699 | 0.84 | LMNA (0.59) | KMT2ACYP2C19CYP3A4CYP1A2TSHR | |
| SCHEMBL1071825 | 0.84 | LMNA (0.59) | KMT2ACYP2C19CYP3A4CYP1A2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025085564-A1 | LYSINE ACETYLTRANSFERASE INHIBITORS | Kronos Bio, Inc. (US) | 2025-04-24 | — | — | WO | disclosed |