Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | SLC22A16 | Q86VW1 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | GALR3 | O60755 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.34 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.34 |
| ▸ | MMP2 | P08253 | 2/20 | 0.34 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.33 |
| ▸ | CPT2 | P23786 | 1/20 | 0.32 |
| ▸ | CPT1A | P50416 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Prolonium SCHEMBL2889745 | 0.93 | MAPT (0.57) | MAPTSLC22A16SMN1; SMN2GALR3BLM | |
| Prolonium SCHEMBL1649967 | 0.89 | MAPT (0.52) | MAPTSLC22A16SMN1; SMN2GALR3BLM | |
| SCHEMBL16405718 | 0.89 | MAPT (0.44) | MAPTSLC22A16SMN1; SMN2GALR3BLM | |
| SCHEMBL15761654 | 0.88 | MAPT (0.42) | MAPTSLC22A16SMN1; SMN2GALR3BLM | |
| Prolonium SCHEMBL5705670 | 0.86 | MAPT (0.50) | MAPTSLC22A16SMN1; SMN2GALR3BLM | |
| Prolonium SCHEMBL1650849 | 0.86 | MAPT (0.50) | MAPTSLC22A16SMN1; SMN2GALR3BLM | |
| Prolonium SCHEMBL11723705 | 0.86 | MAPT (0.50) | MAPTSLC22A16SMN1; SMN2GALR3BLM | |
| Hydrochloric Acid SCHEMBL15557842 | 0.84 | PSMD14 (0.53) | MAPTSLC22A16SMN1; SMN2GALR3BLM | |
| SCHEMBL17430801 | 0.81 | MAPT (0.37) | MAPTSLC22A16PSMD14PLA2G1BMMP2 | |
| SCHEMBL15761655 | 0.81 | PSMD14 (0.55) | MAPTSLC22A16LMNAPSMD14PLA2G1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2814576-B1 | POLYCATIONIC POLYHYDROXYL COMPOUNDS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2017-11-15 | — | — | EP | disclosed |
| US-20150065579-A1 | POLYCATIONIC POLYHYDROXYL COMPOUNDS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2015-03-05 | — | — | US | disclosed |
| WO-2013148613-A1 | POLYCATIONIC POLYHYDROXYL COMPOUNDS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-10-03 | — | — | WO | disclosed |
| US-20100081844-A1 | POLYCATIONIC ORGANIC COMPOUNDS | PNC BANK, NATIONAL ASSOCIATION | 2010-04-01 | — | — | US | disclosed |
| US-7632409-B2 | Cation-exchange displacement chromatography process and cationic organic compounds for use as displacer compounds in cation-exchange displacement chromatography process | SACHEM, INC. (US) | 2009-12-15 | — | — | US | disclosed |
| WO-2007053235-A1 | CATION-EXCHANGE DISPLACEMENT CHROMATOGRAPHY PROCESS AND CATIONIC ORGANIC COMPOUNDS FOR USE AS DISPLACER COMPOUNDS IN CATION-EXCHANGE DISPLACEMENT CHROMATOGRAPHY PROCESS | SACHEM, INC. (US) | 2007-05-10 | — | — | WO | disclosed |
| US-20070102363-A1 | CATION-EXCHANGE DISPLACEMENT CHROMATOGRAPHY PROCESS AND CATIONIC ORGANIC COMPOUNDS FOR USE AS DISPLACER COMPOUNDS IN CATION-EXCHANGE DISPLACEMENT CHROMATOGRAPHY PROCESS | SACHEM, INC. | 2007-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150065579-A1 | POLYCATIONIC POLYHYDROXYL COMPOUNDS | PARG, PAH, CUTA | MAPT 2084/4885SLC22A16 4153/4885SMN1; SMN2 4480/4885 |
| US-20100081844-A1 | POLYCATIONIC ORGANIC COMPOUNDS | OR10J3, ORC3, CCNY | MAPT 4323/4885SLC22A16 1206/4885SMN1; SMN2 4774/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.