SCHEMBL13380992

SCHEMBL13380992

COc1ccc(COC2[C@@H](C)OC(CO[Si](c3ccccc3)(c3ccccc3)C(C)(C)C)[C@@H](O)[C@H]2OCc2ccc(OC)cc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SSTR5 P35346 9/20 0.39
GJB2 P29033 1/20 0.36
GJA1 P17302 1/20 0.36
SSTR3 P32745 4/20 0.35
SSTR2 P30874 2/20 0.35
SSTR1 P30872 1/20 0.35
SSTR4 P31391 1/20 0.35
MCHR1 Q99705 2/20 0.34
SLC5A1 P13866 3/20 0.34
SLC5A2 P31639 3/20 0.34
TACR1 P25103 1/20 0.34
SLC6A2 P23975 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14490088 0.92 SLC6A2 (0.38) SSTR5GJB2SSTR3SSTR2SSTR1
SCHEMBL14221752 0.91 SSTR5 (0.39) SSTR5GJB2GJA1SSTR3SSTR2
SCHEMBL14490089 0.90 SSTR1 (0.40) SSTR5GJB2GJA1SSTR3SSTR2
SCHEMBL13380946 0.90 SSTR5 (0.42) SSTR5GJB2GJA1SSTR3SSTR2
SCHEMBL13855505 0.85 SSTR5 (0.37) SSTR5SSTR3SSTR2SSTR1SSTR4
SCHEMBL6336303 0.84 SSTR4 (0.39) SSTR5GJB2GJA1SSTR3SSTR2
SCHEMBL3156185 0.83 SSTR5 (0.46) SSTR5SSTR3SSTR2SSTR1SSTR4
SCHEMBL13381041 0.83 SSTR5 (0.46) SSTR5SSTR3SSTR2SSTR1SSTR4
SCHEMBL7902126 0.83 SSTR5 (0.46) SSTR5SSTR3SSTR2SSTR1SSTR4
SCHEMBL7030616 0.83 SSTR5 (0.33) SSTR5GJB2GJA1SSTR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100081708-A1 ANTICOAGULANT COMPOUNDS ENDOTIS PHARMA (FR) 2010-04-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100081708-A1 ANTICOAGULANT COMPOUNDS SERPINC1, F2, FUT5 SSTR5 1014/4885GJB2 4413/4885GJA1 4395/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.