Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2837650 | 0.87 | TP53 (0.57) | MAPT | |
| SCHEMBL2841776 | 0.87 | LMNA (0.52) | TSHRL3MBTL1ALDH1A1 | |
| SCHEMBL2847484 | 0.85 | L3MBTL1 (0.59) | TSHRL3MBTL1ALDH1A1MAPT | |
| SCHEMBL2837645 | 0.84 | TSHR (0.54) | TSHRL3MBTL1ALDH1A1 | |
| SCHEMBL2843660 | 0.84 | L3MBTL1 (0.52) | TSHRL3MBTL1ALDH1A1 | |
| SCHEMBL2843070 | 0.83 | L3MBTL1 (0.47) | TSHRL3MBTL1ALDH1A1MAPT | |
| SCHEMBL2837131 | 0.83 | L3MBTL1 (0.56) | TSHRL3MBTL1ALDH1A1 | |
| SCHEMBL2846692 | 0.83 | L3MBTL1 (0.62) | TSHRL3MBTL1ALDH1A1 | |
| SCHEMBL2843212 | 0.82 | TSHR (0.64) | TSHRL3MBTL1MAPT | |
| SCHEMBL13381695 | 0.82 | L3MBTL1 (0.50) | TSHRL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010039911-A1 | CALCILYTIC COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2010-04-08 | — | — | WO | disclosed |