Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.33 |
| ▸ | IARS1 | P41252 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | TRDMT1 | O14717 | 1/20 | 0.31 |
| ▸ | AHCY | P23526 | 1/20 | 0.31 |
| ▸ | AMD1 | P17707 | 1/20 | 0.30 |
| ▸ | TARS1 | P26639 | 2/20 | 0.30 |
| ▸ | DNPH1 | O43598 | 2/20 | 0.30 |
| ▸ | RNMT | O43148 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13384047 | 0.84 | HINT1 (0.34) | — | |
| SCHEMBL26355063 | 0.83 | DOT1L (0.35) | DOT1LIARS1ADORA2AADORA2BTRDMT1 | |
| SCHEMBL13384046 | 0.78 | — | — | |
| SCHEMBL13384048 | 0.76 | P2RY2 (0.43) | — | |
| SCHEMBL29884287 | 0.75 | ADORA2A (0.44) | DOT1LADORA2AADORA2BRNMT | |
| SCHEMBL30324459 | 0.74 | ADORA3 (0.54) | DOT1LADORA2AADORA2BTRDMT1AHCY | |
| SCHEMBL30324473 | 0.74 | ADORA1 (0.55) | DOT1LADORA2AADORA2BAHCYAMD1 | |
| SCHEMBL25679990 | 0.72 | PRMT6 (0.45) | — | |
| SCHEMBL18776429 | 0.71 | ADORA3 (0.31) | DOT1L | |
| SCHEMBL14591326 | 0.71 | KDM4E (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100087634-A1 | Fluorous Oligonucleotide Reagents and Affinity Purification of Oligonucleotides | BERRY & ASSOCIATES, INC. (US) | 2010-04-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087634-A1 | Fluorous Oligonucleotide Reagents and Affinity Purification of Oligonucleotides | DCLRE1B, POLM, FBL | DOT1L 4114/4885IARS1 1106/4885ADORA2A 1832/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.