⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1338682 | 0.83 | NPC1 (0.48) | — | |
| SCHEMBL26156229 | 0.76 | — | — | |
| SCHEMBL26154082 | 0.75 | — | — | |
| SCHEMBL5216740 | 0.72 | — | — | |
| SCHEMBL324930 | 0.72 | DRD2 (0.60) | — | |
| SCHEMBL30752421 | 0.71 | HTR1A (0.48) | — | |
| SCHEMBL4540858 | 0.71 | HTR1A (0.48) | — | |
| SCHEMBL2787499 | 0.71 | HTR1A (0.47) | — | |
| SCHEMBL2406026 | 0.71 | — | — | |
| SCHEMBL2867964 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1380121-B1 | PROCESS TO PREPARE OXAZOLIDINONES | PHARMACIA & UPJOHN CO LLC (US) | 2007-09-26 | — | — | EP | disclosed |
| US-7087784-B2 | Process to prepare oxazolidinones | PHARMACIA & UPJOHN (US) | 2006-08-08 | — | — | US | disclosed |
| US-6887995-B2 | Process to prepare oxazolidinones | PHARMACIA & UPJOHN COMPANY (US) | 2005-05-03 | — | — | US | disclosed |
| US-20040220407-A1 | Process to prepare oxazolidinones | PERRAULT WILLIAM R | 2004-11-04 | — | — | US | disclosed |
| EP-1380121-A2 | PROCESS TO PREPARE OXAZOLIDINONES | PHARMACIA & UPJOHN COMPANY (US) | 2004-01-14 | — | — | EP | disclosed |
| US-20020169312-A1 | Process to prepare oxazolidinones | PHARMACIA & UPJOHN COMPANY | 2002-11-14 | — | — | US | disclosed |
| WO-2002085849-A2 | PROCESS TO PREPARE OXAZOLIDINONES | PHARMACIA & UPJOHN COMPANY (US) | 2002-10-31 | — | — | WO | disclosed |