Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 4/20 | 0.40 |
| ▸ | CES2 | O00748 | 2/20 | 0.39 |
| ▸ | CES1 | P23141 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30753199 | 1.00 | TSHR (0.43) | TSHRSMN1; SMN2ALDH1A1CYP11B1CYP11B2 | |
| SCHEMBL6561685 | 0.95 | TSHR (0.46) | TSHRSMN1; SMN2ALDH1A1MAOBCES2 | |
| SCHEMBL8257796 | 0.83 | TSHR (0.47) | TSHRSMN1; SMN2ALDH1A1MAOBCES2 | |
| SCHEMBL5461436 | 0.83 | HTT (0.41) | TSHRSMN1; SMN2ALDH1A1MAOBCES2 | |
| SCHEMBL24445879 | 0.83 | MEN1 (0.42) | TSHRSMN1; SMN2ALDH1A1MAOBCES2 | |
| SCHEMBL9025859 | 0.83 | KDM4E (0.44) | TSHRSMN1; SMN2MAOBCES2CES1 | |
| SCHEMBL8257879 | 0.83 | TSHR (0.43) | TSHRSMN1; SMN2ALDH1A1MAOBCES2 | |
| SCHEMBL9038615 | 0.81 | ALDH1A1 (0.43) | TSHRSMN1; SMN2ALDH1A1MAOBCES2 | |
| SCHEMBL8282300 | 0.81 | TSHR (0.39) | TSHRSMN1; SMN2ALDH1A1MAOBCES2 | |
| SCHEMBL246839 | 0.81 | CES2 (0.39) | TSHRSMN1; SMN2ALDH1A1MAOBCES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 174 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104844412-B | A kind of preparation method of 1,2,4-trifluoro-benzene | 浙江林江化工股份有限公司 | 2016-06-08 | — | — | CN | claimed |
| CN-104844412-A | Preparation method of 1,2,4-trifluorobenzene | ZHEJIANG LINJIANG CHEMICAL CO LTD | 2015-08-19 | — | — | CN | claimed |
| US-8952083-B2 | Fluorocopolymer composition and its production process | ASAHI GLASS COMPANY, LIMITED (JP) | 2015-02-10 | — | — | US | claimed |
| CN-101244994-B | Novel method for producing 2,4,5-trifluoro benzene acetic acid | CHANGZHOU YABANG PHARMACEUTICAL CO LTD | 2013-02-13 | — | — | CN | claimed |
| WO-2010138807-A1 | FLUORINATED SILYLETHYNYL PENTACENE COMPOUNDS AND COMPOSITIONS AND METHODS OF MAKING AND USING THE SAME | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2010-12-02 | — | — | WO | claimed |
| JP-2184650-A | — | — | None | — | — | JP | disclosed |
| WO-2025077773-A1 | NOVEL TYPE I TOPOISOMERASE INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翊维康医药有限责任公司 | 2025-04-17 | — | — | WO | disclosed |
| CN-119317289-A | Perovskite quantum dot Micro-LED based on double ligand strategy and preparation method thereof | 新型显示与视觉感知石城实验室 | 2025-01-14 | — | — | CN | disclosed |
| CN-117603048-A | Preparation method of ethyl 2,4, 5-trifluorobenzoyl acetate | 安徽森吉制药有限公司 | 2024-02-27 | — | — | CN | disclosed |
| CN-117088869-A | 3CL protease inhibitor and preparation method and application thereof | 上海翊石医药科技有限公司 | 2023-11-21 | — | — | CN | disclosed |
| US-11584744-B2 | Inhibitors of type 1 methionyl-tRNA synthetase and methods of using them | UNIVERSITY OF WASHINGTON (US) | 2023-02-21 | — | — | US | disclosed |
| US-11584744-B2 | Inhibitors of type 1 methionyl-tRNA synthetase and methods of using them | UNIVERSITY OF WASHINGTON (US) | 2023-02-21 | — | — | US | disclosed |
| WO-1996004247-A1 | PROCESS FOR MAKING ANTIMICROBIAL COMPOUNDS | THE PROCTER & GAMBLE COMPANY (US) | 1996-02-15 | — | — | WO | disclosed |
| EP-0365913-B1 | Substituted 2-aminothiazoles | BAYER AG (DE) | 1993-11-18 | — | — | EP | disclosed |
| US-5142092-A | Chemical intermediate for making fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 1992-08-25 | — | — | US | disclosed |
| EP-0365914-B1 | FLUORINE-CONTAINING ACETOPHENONES OPTIONALLY HALOGENATED IN THE CH3-GROUP, AND THEIR PREPARATION FROM FLUORINATED BENZONITRILES | BAYER AG (DE) | 1992-07-22 | — | — | EP | disclosed |
| US-5104879-A | ANTIMYCOTICALLY ACTIVE SUBSTITUTED 2-AMINOTHIAZOLES | BAYER AKTIENGESELLSCHAFT (DE) | 1992-04-14 | — | — | US | disclosed |
| JP-H02184650-A | 2,4,5-TRIFLUOROACETOPHENONE, PRODUCTION THEREOF AND PRODUCTION OF 2,4,5-TRIFLUOROBENZOIC ACID | CENTRAL GLASS CO LTD | 1990-07-19 | — | — | JP | disclosed |
| EP-0365914-A2 | Fluorine-containing acetophenones optionally halogenated in the CH3-group, and their preparation from fluorinated benzonitriles | BAYER AG (DE) | 1990-05-02 | — | — | EP | disclosed |
| EP-0365913-A2 | Substituted 2-aminothiazoles | BAYER AG (DE) | 1990-05-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11584744-B2 | Inhibitors of type 1 methionyl-tRNA synthetase and methods of using them | AARS1, EMG1, GARS1 | TSHR 1215/4885SMN1; SMN2 1129/4885ALDH1A1 1461/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.